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Blockchain in Clinical Trials Companies and Company Profile

Date : 17 October 2025

Top Innovator in the Blockchain in Clinical Trials Market

Blockchain in Clinical Trials Market Companies

Company Profile

Company Headquarters Annual Revenue (USD) Revenue Year
Oracle Corporation Austin, Texas, USA $57.4 billion FY2025
Guardtime Tallinn, Estonia $10 million (est.) 2023
Chronicled (MediLedger) San Francisco, California, USA $15 million (est.) 2023
Hashed Health Nashville, Tennessee, USA $10–12 million (est.) 2023

Oracle Corporation

Overview

  • Headquarters: Austin, Texas, USA

  • Founded: 1977 by Larry Ellison, Bob Miner, and Ed Oates

  • Oracle is a global leader in enterprise software, database systems, and cloud infrastructure, with a strong focus on cloud computing, AI infrastructure, and SaaS solutions.

  • The company generated around $57.4 billion in revenue in FY2025, driven by strong growth in its cloud business.

Products

  • Oracle Cloud Infrastructure (OCI) – offering compute, storage, networking, and AI capabilities.

  • Fusion Cloud Applications – includes ERP, HCM, and CX solutions.

  • Autonomous Database and analytics software for enterprise data management.

Strengths

  • Large and loyal enterprise customer base across industries.

  • Strong integration between database, cloud, and SaaS products.

  • Expanding partnerships in multicloud and AI sectors.

Opportunities

  • Increasing demand for AI infrastructure and cloud computing.

  • Expansion of industry-specific cloud solutions (e.g., healthcare, finance).

  • Potential growth through strategic acquisitions and alliances.

Challenges

  • Fierce competition from AWS, Microsoft Azure, and Google Cloud.

  • High costs related to cloud infrastructure expansion.

  • Transitioning legacy customers to the cloud efficiently.

Recent Developments

  • Announced major AI infrastructure partnerships with global technology firms.

  • Expanded OCI data centers worldwide to support growing demand.

  • Reported record growth in cloud and AI-driven services in FY2025.

Guardtime

Overview

  • Headquarters: Tallinn, Estonia

  • Founded: 2007

  • Guardtime is a cybersecurity company specializing in blockchain-based data integrity solutions.

  • Known for developing the KSI Blockchain, used by governments and enterprises for secure data verification.

Products

  • KSI Blockchain – ensures data integrity and authenticity across systems.

  • Digital integrity and compliance tools for enterprises.

  • Advanced cryptographic verification systems for critical sectors.

Strengths

  • Proven, scalable blockchain technology used in national-level systems.

  • Strong reputation for security and cryptographic innovation.

  • Partnerships with governments and global enterprises.

Opportunities

  • Growing demand for digital trust and data integrity across industries.

  • Expansion into space, defense, and healthcare sectors.

  • Rising adoption of blockchain in cybersecurity frameworks.

Challenges

  • Complex integration with existing legacy systems.

  • Limited public awareness compared to conventional blockchain brands.

  • Lengthy adoption cycles in highly regulated industries.

Recent Developments

  • Expanded use of KSI Blockchain in data integrity and compliance solutions.

  • Introduced enhanced services for space and satellite data verification.

  • Invested in R&D to extend its cryptographic technology portfolio.

Medicalchain

Overview

  • Headquarters: Chiasso, Switzerland

  • Founded: 2016

  • Medicalchain develops blockchain-powered healthcare solutions focused on patient data management and telemedicine.

  • The company enables patients to control and share their medical records securely.

Products

  • Blockchain-based electronic health record (EHR) system.

  • MyClinic, a telemedicine platform for virtual consultations.

  • APIs for secure and transparent medical data sharing.

Strengths

  • Strong focus on patient empowerment and data ownership.

  • Early adoption of blockchain in healthcare record management.

  • Scalable telehealth solution with real-world deployment.

Opportunities

  • Increasing acceptance of telemedicine globally.

  • Rising need for secure patient data interoperability.

  • Potential collaborations with healthcare providers and insurers.

Challenges

  • Competition from established electronic health record (EHR) systems.

  • Complex healthcare regulations across different countries.

  • Monetization challenges in the emerging telehealth market.

Recent Developments

  • Expanded access to MyClinic in multiple international markets.

  • Continued development of blockchain-based data consent tools.

  • Strengthened focus on data privacy and interoperability compliance.

Triall

Overview

  • Headquarters: Maarssen, Netherlands

  • Founded: 2018

  • Triall integrates blockchain technology into clinical trial management systems to enhance transparency and data integrity.

  • It provides a modular eClinical platform to streamline research operations.

Products

  • Verial eTMF – blockchain-secured electronic trial master file system.

  • eClinical tools for decentralized and hybrid clinical trials.

  • Data verification and audit trail services for research organizations.

Strengths

  • Specialized focus on clinical data integrity and traceability.

  • Experienced team with deep expertise in clinical operations.

  • Strong partnerships within the life sciences and biotech sectors.

Opportunities

  • Growing trend toward decentralized and hybrid clinical trials.

  • Regulatory support for data transparency in research.

  • Potential collaborations with contract research organizations (CROs).

Challenges

  • High competition from large clinical trial software providers.

  • Need for continuous validation of blockchain technologies.

  • Limited resources for global market expansion.

Recent Developments

  • Launched new blockchain-driven eClinical software solutions.

  • Expanded its partnership network to include CROs and data partners.

  • Continued innovation in data verification for decentralized trials.

Chronicled (MediLedger)

Overview

  • Headquarters: San Francisco, California, USA

  • Founded: 2014

  • Chronicled operates the MediLedger Network, a blockchain platform for secure and automated pharmaceutical supply chain management.

  • Focuses on data alignment and revenue management for the life sciences industry.

Products

  • MediLedger Network – enables contract, pricing, and chargeback automation.

  • Compliance tools for pharmaceutical supply chain traceability.

  • Secure blockchain infrastructure for multi-party transactions.

Strengths

  • Strong network of pharmaceutical manufacturers and distributors.

  • Proven use cases for reducing pricing errors and revenue leakage.

  • Deep expertise in regulated healthcare data management.

Opportunities

  • Expansion in pharmaceutical compliance and DSCSA traceability.

  • Potential adoption in global supply chain systems.

  • Opportunity to scale beyond pharma to other life sciences domains.

Challenges

  • Integration complexities with existing ERP and logistics systems.

  • Maintaining governance and trust within network participants.

  • High cost and time required to onboard new partners.

Recent Developments

  • Expanded its MediLedger services for pricing and contract management.

  • Strengthened its network partnerships with major life sciences players.

  • Continued innovation to support DSCSA compliance initiatives.

Hashed Health

Overview

  • Headquarters: Nashville, Tennessee, USA

  • Founded: 2016

  • Hashed Health is a venture studio that builds blockchain-based healthcare solutions.

  • It focuses on credentialing, supply-chain transparency, and value-based care.

Products

  • ProCredEx – a blockchain-powered professional credentialing platform.

  • Peer Supply – enables transparent supply-chain data sharing.

  • Pathmaker – supports value-based healthcare program management.

Strengths

  • Strong network of healthcare system partners and innovators.

  • Deep expertise in healthcare data ecosystems and blockchain technology.

  • Proven ability to incubate and scale successful startups.

Opportunities

  • Rising demand for verified digital credentials in healthcare.

  • Growing focus on data-sharing and supply-chain resilience.

  • Potential partnerships with payers and healthcare providers.

Challenges

  • Competition from traditional SaaS vendors.

  • Balancing collaboration and monetization in consortia projects.

  • Limited scalability due to venture studio business model.

Recent Developments

  • Expanded the Peer Supply platform for supply-chain visibility.

  • Enhanced ProCredEx adoption among U.S. healthcare institutions.

  • Announced new venture projects in digital identity and data transparency.

Factom

Overview

  • Headquarters: Austin, Texas, USA

  • Founded: 2014

  • Factom developed one of the first enterprise-grade blockchain protocols for data integrity and document verification.

  • The company filed for bankruptcy in 2020 after financial challenges but remains notable in blockchain history.

Products

  • Factom Protocol – for data notarization and audit trail generation.

  • APIs for secure document verification.

  • Blockchain anchoring solutions for enterprise systems.

Strengths

  • Early pioneer in blockchain data integrity solutions.

  • Robust, open-source architecture suitable for public and private uses.

  • Proven applications in government and enterprise pilot programs.

Opportunities

  • Reuse of protocol technology in newer blockchain systems.

  • Integration into auditing, finance, and record-keeping industries.

  • Potential for revival or technology acquisition by other firms.

Challenges

  • Bankruptcy halted corporate operations and innovation.

  • Lost market share to newer blockchain protocols.

  • Limited funding and active development since 2020.

Recent Developments

  • Ceased major operations following bankruptcy proceedings.

  • Technology continues to be referenced in blockchain audit frameworks.

  • Former projects have influenced data integrity applications in other industries.

Market Forecast

The global blockchain in clinical trials market is on an upward trajectory, poised to generate substantial revenue growth, potentially climbing into the hundreds of millions over the forecast years from 2025 to 2034. This surge is attributed to evolving consumer preferences and technological advancements reshaping the industry.

Rising Adoption of Decentralized Technologies: Decentralized blockchain systems are being adopted by sponsors, CROs, and pharmaceutical companies as clinical trial stakeholders in an effort to enhance safe cooperative data exchange. This change reduces data bottlenecks and increases trust across international networks by enabling multi-site trials to function more transparently. Organizations are expanding pilots into practical trials where blockchain guarantees data integrity across stakeholders, providing that adoption is no longer merely theoretical.

  • In June 2024, LabTrace, in collaboration with King College London, announced the completion of its first experimental medicine study using a blockchain-based notarization tool on Algorand, enhancing transparency and data authentication in Parkinson disease research.

Growing Focus on Patient-Centric Trials: Trials are becoming more efficient and patient-friendly by utilizing blockchain technology for eConsent recruitment and consent tracking. Participants experience transparent usage, regain control over their data, and feel more at ease knowing that their information is reliable and unchangeable. Around the world, this increases trial participation, lowers dropout rates, and fosters trust.

  • In March 2024, PharmaLedger Association introduced its Decentralized Trials Project, focused on blockchain-based eEnrollment, eConsent, and IoT integration to empower patient participation and transparency in trial processes.

Latest Announcement by Industry Leaders

  • In April 2025, Netra Mark Holdings Inc. announced a global agreement with Worldwide Clinical Trials to integrate its AI-powered NetraAI platform into clinical trial design and optimization. George Achilleos, CEO of Netra Mark, stated: “By integrating NetraAI with Worldwide global clinical infrastructure, we are enabling sponsors to better understand patient response dynamics, reduce placebo variability, and improve the likelihood of regulatory success.”
  • In August 2025, Wellgistics debuted an XRP Ledger-based payments system for independent U.S. pharmacies. Brian Norton, CEO of Wellgistics, said: “Independent pharmacy owners are far more forward-thinking than many realize. They see the power of blockchain and understand how transformative this will be as it scales across the industry.”

Recent Developments in the Blockchain in Clinical Trials Market

  • In 2025, Magnifico insights highlighted notable developments like MediLedger expanding into clinical trials (audit trails), Trials.ai automating protocol/data capture, and ongoing pilot projects by Pfizer and Roche for consent and data provenance.
  • In 2024, AstraZeneca & IBM Collaboration implemented a decentralized ledger to manage oncology trial processes, accelerating tracking of patient consent and data sharing—reportedly cutting administrative tasks by 30%.

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