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Diabetic Neuropathy Treatment Market Surges 7.75% CAGR by 2034

Diabetic Neuropathy Treatment Market AI, Robotics and Smart Dispensing Systems

Projections indicate that, the global diabetic neuropathy treatment market will increase from USD 4.71 billion in 2024 to USD 9.93 billion by 2034, experiencing a CAGR of 7.75% over the next 10 years. The diabetic neuropathy treatment market is expanding due to increasing incidences of diabetes as well as rising gene therapies. North America led the market due to the presence of advanced industries.

Category: Therapeutic Area Insight Code: 5608 Format: PDF / PPT / Excel

Kesiya Chacko

Principal Consultant

Aditi Shivarkar

Reviewed By

Global Diabetic Neuropathy Treatment Market Size, Insights, Forecast and Competitive Strategies

The global diabetic neuropathy treatment market size is calculated at USD 4.71 in 2024, grew to USD 5.07 billion in 2025, and is projected to reach around USD 9.93 billion by 2034. The market is expanding at a CAGR of 7.75% between 2025 and 2034.

Diabetic Neuropathy Treatment Market Size 2024 - 2034

Key Takeaways

  • North America dominated the global diabetic neuropathy treatment market in 2024.
  • Europe is expected to be the fastest-growing during the forecast period.
  • By disorder type, the peripheral neuropathy segment dominated the market in 2024.
  • By disorder type, the autonomic neuropathy segment is estimated to be the fastest growing at a notable CAGR during the forecast period.
  • By drug class type, the non-steroidal anti-inflammatory drugs (NSAIDs) segment dominated the market in 2024.
  • By drug class type, the opioid segment is anticipated to grow significantly during the forecast period.
  • By distribution channel type, the hospital pharmacies segment dominated the global diabetic neuropathy treatment market in 2024.
  • By distribution channel type, the online segment is predicted to grow significantly during the forecast period.

Market Overview

Over 90% of diabetic patients are affected by diabetic neuropathy, which is a type of complication associated with both types of diabetes. The main symptom is pain, and its mechanism is not fully known, but it is considered that it may be due to the toxic effects of hyperglycemia. The use of medications to alleviate pain and improve glycemic control as a prophylactic therapy is most commonly used in diabetic neuropathy management. The use of NSAIDs to reduce the pain is the first-line treatment option. Furthermore, the opioids use is also increasing.  Similarly, capsaicin cream and lidocaine patches are also being used.

Key Metrics and Overview

Metric Details
Market Size in 2024 USD 4.71 Billion
Projected Market Size in 2034 USD 9.93 Billion
CAGR (2025 - 2034) 7.75%
Leading Region North America
Market Segmentation By Disorder Type, By Drug Class, By Distribution Channel and By Region
Top Key Players Pfizer. Inc, Abbott, Janssen Pharmaceuticals, Inc, Eli Lilly and Company, Glenmark Pharmaceuticals Ltd, Lupin Pharmaceuticals, Novartis, Astellas Pharma Inc, Boehringer Ingelheim GmbH
  • In October 2024, a collaboration between Alkem Laboratories and US-based Sonnet BioTherapeutics was announced, where a new drug, 'SON-080', will be developed and commercialized for diabetic peripheral neuropathy in India. Their main objective is to enhance the treatment options for diabetic peripheral neuropathy patients in India.
  • In October 2023, the collaboration between the Ohio State University Wexner Medical Center and the College of Medicine received a $3.6 million award, which will permit their researchers from fields like neuroscience, neurosurgery, and neurology to test a novel diagnosis and treatment combination for painful diabetic neuropathy from the National Institutes of Health. Here, the spinal cord stimulation will be combined with measurement of small fiber nerve activity by utilizing a patent-pending device known as Detecting Early Neuropathy (DEN).

AI Integration in the Diabetic Neuropathy Treatment Market

By utilizing AI the diabetic neuropathy can be easily diagnosed and predicted. Thus, a new system was developed that helped in the diagnostic process. This system consisted of various parameters such as HbA1c levels, diabetes duration, fasting blood glucose, sign scores based on the Michigan questionnaire, symptom scores based on the Michigan questionnaire, proteinuria, and serum creatinine. The system also enhanced the accuracy during the diagnosis. Furthermore, models for glycemic management were also developed. These provided the clinicians a fast and accurate assessment of the patient's condition as well as in formulating the treatment plans.

Market Dynamics

Driver

Increasing Occurrences of Diabetes

The incidence of diabetes within the population is rising. This, in turn, increases the complications associated with it due to a lack of early detection. Thus, the demand for early detection as well as treatment options also increases. At the same time, the neuropathy also leads to worsening of the patient's condition. Hence, to manage the pain as well as protect the nerves from damage, new treatment options are being developed. Thus, all these factors, along with the increasing awareness, are driving the diabetic neuropathy treatment market growth.

Estimated Rates of Patients with Diabetes

The graph represents the comparison between the number of patients suffering from diabetes in the year of 2024 and 2045. It indicates that there will be a rise in the patients with diabetes in 2045. Hence, it increases the demand for new treatment as well as diagnostic options for the effective management of diabetic neuropathy along with diabetes. Thus, this in turn will ultimately promote the market growth.

Restraint

Lack of Early Diagnosis

The diabetes neuropathy in most cases is not detected. This leads to the worsening of the conditions. It can cause permanent damage to the nerves, which in turn can cause more complications. Moreover, in some cases, the treatment can be ineffective due to its progression. Thus, to manage diabetic neuropathy, early detection is needed with proper management of the condition.

Opportunity

Increasing Gene Therapies

Most of the treatments of diabetic neuropathy focus on pain management and not on its treatment. Thus, the demand for effective treatment options rises. Therefore, the use of gene therapy, which focuses on the root cause of the neuropathy, is increasing. It helps to regenerate the damaged nerves as well as protect them. It can also be used in personalized treatment plans, depending on the patient’s genetic characteristics. Thus, this promotes the diabetic neuropathy treatment market growth.

For instance,

  • In May 2025, a gene therapy, which was developed by Helixmith, known as Engensis, initiated dosing patients in a new study after its success in its first phase 3 trial.

Segmental Insights

Peripheral Neuropathy Segment Dominated

By disorder type, the peripheral neuropathy segment dominated the market in 2024. The peripheral neuropathy was detected in most of the patients due to its early diagnosis. Furthermore, the complications associated with it also contributed to the diabetic neuropathy treatment market growth.

Autonomic Neuropathy Segment: Fastest Growing

By disorder type, the autonomic neuropathy segment is estimated to be the fastest growing at a notable CAGR during the forecast period. Due to increasing awareness, autonomic neuropathy is being effectively detected through early diagnosis. This, in turn, increases the demand for its management.

The Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) Segment Led in 2024

By drug class type, the non-steroidal anti-inflammatory drugs (NSAIDs) segment dominated the market in 2024. The NSAIDs were used in the management of the mild to moderate pain associated with diabetic neuropathy. At the same time, its availability and affordability enhanced the market growth.

Opioid Segment: Significantly Growing

By drug class type, the opioid segment is anticipated to grow significantly during the forecast period. The use of opioids is rising in the management of pain in severe conditions or when NSAIDs are ineffective in diabetic neuropathy. Thus, its demand is rising in the market.

Hospital Pharmacies Segment Dominated

By distribution channel type, the hospital pharmacies segment dominated the global diabetic neuropathy treatment market in 2024. The hospital pharmacies provided the advanced therapies for the treatment of diabetic neuropathy. Moreover, various treatment regimens were also offered in the severe cases, which resulted in promoting the market growth.

Online Segment: Significantly Growing

By distribution channel type, the online segment is predicted to grow significantly during the forecast period. The online distribution channel offers a wide range of products at reasonable prices. It also provides easy access and home deliveries, enhancing patient convenience and satisfaction.

Advanced Industries Drives North America

North America dominated the diabetic neuropathy treatment market in 2024. North America consisted of well-developed industries along with skilled personnel, as well as technological advancements. This increased the number of innovations for the diagnosis and treatment of diabetic neuropathy, contributing to the market growth.

The U.S. Diabetic Neuropathy Treatment Market Trends

Due increasing demand for early diagnosis and treatment of diabetic neuropathy, the industries are focused on the development of the same. These are also supported by governmental funding or investments.

The Canada Diabetic Neuropathy Treatment Market Trends

The industries in Canada are using the technologies to enhance diagnostic techniques using AI. Furthermore, new treatments are also being developed. This, in turn, increases the collaboration within the companies.

Europe Driven by Rising Awareness

Europe is estimated to host the fastest-growing diabetic neuropathy treatment market during the forecast period. Europe is experiencing a rise in awareness due to increasing programs and campaigns about the early detection of diabetic neuropathy. Thus, this enhances the market growth.

The Germany Diabetic Neuropathy Treatment Market Trends

Various programs are being conducted by the government as well as the private sector for the early diagnosis of neuropathy. This, in turn, increases the demand for the diagnosis and treatment of the same.

The UK Diabetic Neuropathy Treatment Market Trends

Due to the rising awareness through the campaigns, the demand for new and effective treatments is rising, along with the use of personalized medication. At the same time, the government is also supporting these awareness programs and campaigns.

Increasing Diabetes Boosts Asia Pacific

Asia Pacific is expected to grow significantly in the diabetic neuropathy treatment market during the forecast period. The number of patients with diabetes is rising rapidly in the Asia Pacific. This increases the use as well as the demand for new diagnostic and treatment approaches for diabetic neuropathy. This promotes the market growth.

The China Diabetic Neuropathy Treatment Market Trends

The number of patients with diabetes is increasing in China. Thus, this increases the production of new treatment approaches as well as research in the industries and institutes. This is further supported by the government.

The India Diabetic Neuropathy Treatment Market Trends

India is facing rapid growth in diabetic patients, increasing the risk of diabetic neuropathy. Thus, with the help of government support, the healthcare sector is focusing on the development of new treatments as well as diagnostic methods for the same at affordable prices.

Top Companies in the Diabetic Neuropathy Treatment Market

Diabetes Care Devices Market Companies

Latest Announcements by Industry Leaders

  • In May 2025, the CEO, ACRB, DC of The Wellness Center Health & Therapy, Dr. Stacy Harris, stated that the warning signs are dismissed by most of the patients, considering it a part of getting older. Their mission is to increase awareness among patients by providing clear, objective data and helping them before permanent nerve damage.
  • In April 2025, Dr. Khosla, who utilizes various techniques for neuropathy, including non-invasive treatments such as capsaicin patches, stated that, the capsaicin molecule is removed from the chili peppers, it is then hyper-concentrated to an 8% solution, and finally is wrapped around the foot of the patient for about 30 minutes. He further stated that this can minimize the symptoms of neuropathy by 30% in just 2 weeks.

Recent Developments in the Diabetic Neuropathy Treatment Market

  • In April 2025, data was compiled by MIRA Pharmaceuticals, Inc., which is a clinical-stage pharmaceutical company that develops novel therapeutics for neurologic and neuropsychiatric disorders, for the demonstration of the oral ketamine analog, that is Ketamir-2, for its efficacy in a validated animal model of diabetic neuropathy.
  • In April 2025, a trial exploring spinal cord stimulation (SCS) as a holistic treatment for painful diabetic peripheral neuropathy (pDPN) was presented by the researchers at the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego. As per the findings, the pain can be minimized along with symptoms, as well as neurological recovery can be enhanced using SCS.

Segments Covered in the Report

By Disorder Type

  • Peripheral Neuropathy
  • Autonomic Neuropathy
  • Proximal Neuropathy
  • Focal Neuropathy

By Drug Class

  • Capsaicin
  • Opioid
    • Morphine
    • Others
  • Non-Steroidal Anti-inflammatory Drugs (NSAIDs)
    • Ibuprofen
    • Naproxen
    • Others
  • Antidepressants
    • Tricyclic Antidepressants (TCAs)
      • Amitriptyline
      • Imipramine
      • Others
    • Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)
      • Duloxetine
      • Others 
    • Selective Serotonin Reuptake Inhibitors (SSRIs)
      • Citalopram
      • Paroxetine
      • Others
    • Anticonvulsant Drugs
      • Gabapentin
      • Pregabalin
      • Topiramate
      • Others
  • Other

By Distribution Channel

  • Hospitals Pharmacies
  • Retail Pharmacies
  • Other

By Region

  • North America
    • U.S.
    • Canada
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Thailand
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Sweden
    • Denmark
    • Norway
  • Latin America
    • Brazil Mexico
    • Argentina
  • Middle East and Africa (MEA)
    • South Africa
    • UAE
    • Saudi Arabia
    • Kuwait
  • Last Updated: 09 May 2025
  • Report Covered: [Revenue + Volume]
  • Historical Year: 2021-2023
  • Base Year: 2024
  • Estimated Years: 2025-2034

Meet the Team

Kesiya Chacko is a healthcare market research expert with 4+ years of experience, specializing in analyzing industry trends, assessing market opportunities, and providing actionable insights for businesses in healthcare sectors.

Learn more about Kesiya Chacko

Aditi Shivarkar, with over 14 years of experience in consumer goods, leads research at Towards Consumer Goods, ensuring precise, actionable insights on trends, consumer preferences, and sustainable packaging for businesses.

Learn more about Aditi Shivarkar

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FAQ's

Diabetic neuropathy is a complication associated with diabetes that causes damage to the nerves.

Pfizer Inc. is the major player in the market.

Ministry of Health and Family Welfare, Government of India, National Institutes of Health, FDA, WHO, PIB, CDC.