Towards Healthcare
CAR T-Cell Therapies Market to Rise at 29.8% CAGR by 2035

CAR T-Cell Therapy Market Expands with Rising Cancer Burden

Projections indicate that, the global CAR T-cell therapy market will increase from USD 12.88 billion in 2025 to USD 193.6 billion by 2035, experiencing a CAGR of 29.80% over the next 10 years, the CAR T-cell therapy market saw major advancements: MGM Medical College in India introduced the therapy for blood cancer, Vyriad teamed with Novartis on in vivo CAR T-cell innovations, and Moffitt Cancer Center partnered with AstraZeneca to accelerate T-cell therapy development.

Last Updated : 11 December 2025 Category: Therapeutic Area Insight Code: 5028 Format: PDF / PPT / Excel

Executive Summary

  • Market Overview
  • Key Findings
  • Market Trends
  • Strategic Recommendations

Introduction

  • Definition of CAR T-Cell Therapy
  • Scope of the Report
  • Research Methodology
  • Market Segmentation

Market Dynamics

  • Drivers
    • Increasing Cancer Incidence
    • Technological Advancements
    • Growing Investment in Research and Development
  • Restraints
    • High Treatment Costs
    • Complex Manufacturing Processes
  • Opportunities
    • Expanding Applications
    • Emerging Markets
  • Challenges
    • Regulatory Hurdles
    • Side Effects and Safety Concerns

Market Analysis

  • Historical Market Size and Growth
  • Market Forecast
  • Market Share Analysis
  • Pricing Analysis

Segments Analysis

By Drug Type

  • Axicabtagene Ciloleucel
  • Tisagenlecleucel
  • Brexucabtagene Autoleucel
  • Others

By Indication

  • Lymphoma
  • Acute Lymphocytic Leukemia
  • Chronic Lymphocytic Leukemia (CLL)
  • Multiple Myeloma (MM)
  • Others

By End User

  • Hospitals
  • Cancer Treatment Centers

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • The Middle East and Africa

Cross-Segments Analysis

By Drug Type

  • Axicabtagene Ciloleucel
    • By Indication
      • Lymphoma: High revenue and volume due to FDA approvals and clinical efficacy.
      • Acute Lymphocytic Leukemia (ALL): Moderate revenue and volume, significant market in the U.S. and Europe.
      • Chronic Lymphocytic Leukemia (CLL): Lower revenue, less prevalent indication.
      • Multiple Myeloma (MM): Emerging market with increasing volume and value as approvals expand.
      • Others: Includes niche indications with smaller market share.
    • By End User
      • Hospitals: Significant revenue due to high costs of therapy and large patient base.
      • Cancer Treatment Centers: Growing volume as specialized centers adopt this therapy.
    • By Geography
      • North America: Dominates market value and volume due to extensive clinical use and high adoption.
      • Europe: Growing market, with Germany and the UK leading in adoption.
      • Asia-Pacific: Emerging market with increasing adoption in China and Japan.
      • Latin America: Smaller market with growth potential.
      • The Middle East and Africa: Niche market with expanding opportunities.
  • Tisagenlecleucel
    • By Indication
      • Lymphoma: High market value and volume; well-established in various regions.
      • Acute Lymphocytic Leukemia (ALL): Strong presence in North America and Europe.
      • Chronic Lymphocytic Leukemia (CLL): Moderate market share; emerging in new regions.
      • Multiple Myeloma (MM): Increasing market with growing clinical evidence.
      • Others: Niche applications with developing market presence.
    • By End User
      • Hospitals: High revenue due to comprehensive therapy administration.
      • Cancer Treatment Centers: Increasing volume with specialized treatment settings.
    • By Geography
      • North America: Leading market with high adoption rates and significant revenue.
      • Europe: Growing market with strong performance in major countries.
      • Asia-Pacific: Emerging market with rising adoption, especially in China and Japan.
      • Latin America: Developing market with gradual growth.
      • The Middle East and Africa: Limited but growing presence.
  • Brexucabtagene Autoleucel
    • By Indication
      • Lymphoma: Moderate market value and volume; expanding indications.
      • Acute Lymphocytic Leukemia (ALL): Emerging presence, with growing market potential.
      • Chronic Lymphocytic Leukemia (CLL): Developing market; limited by clinical use.
      • Multiple Myeloma (MM): Growing indication with increasing market share.
      • Others: Niche indications with smaller market impact.
    • By End User
      • Hospitals: Significant revenue from high-cost therapies.
      • Cancer Treatment Centers: Growing volume due to specialized treatment focus.
    • By Geography
      • North America: Leading market with high adoption and revenue.
      • Europe: Growing market with expanding usage.
      • Asia-Pacific: Emerging market with increasing adoption.
      • Latin America: Developing market with gradual growth.
      • The Middle East and Africa: Limited market presence but potential for expansion.
  • Others
    • By Indication
      • Lymphoma: Smaller revenue and volume compared to leading drugs, but growing.
      • Acute Lymphocytic Leukemia (ALL): Niche applications with developing market share.
      • Chronic Lymphocytic Leukemia (CLL): Limited market presence.
      • Multiple Myeloma (MM): Emerging with potential for increased market share.
      • Others: Various indications with small but growing market segments.
    • By End User
      • Hospitals: Revenue generation from high-cost therapies.
      • Cancer Treatment Centers: Increasing volume with specialized treatment offerings.
    • By Geography
      • North America: Developing market with high adoption rates.
      • Europe: Emerging market with growing revenue.
      • Asia-Pacific: Increasing market share with rising adoption.
      • Latin America: Small but expanding market.
      • The Middle East and Africa: Limited presence with potential for future growth.

By Indication

  • Lymphoma
    • By Drug Type
      • Axicabtagene Ciloleucel: High market value and volume.
      • Tisagenlecleucel: Significant market share with high adoption.
      • Brexucabtagene Autoleucel: Moderate market presence; expanding.
      • Others: Growing market for emerging therapies.
    • By End User
      • Hospitals: Major revenue due to extensive treatment.
      • Cancer Treatment Centers: Increasing volume as specialty centers adopt therapy.
    • By Geography
      • North America: Dominates in market value and volume.
      • Europe: Significant market presence, especially in Germany and the UK.
      • Asia-Pacific: Emerging market with growing adoption.
      • Latin America: Developing market with potential growth.
      • The Middle East and Africa: Niche market with expanding opportunities.
  • Acute Lymphocytic Leukemia (ALL)
    • By Drug Type
      • Axicabtagene Ciloleucel: Strong market presence with growing adoption.
      • Tisagenlecleucel: High market value and volume.
      • Brexucabtagene Autoleucel: Emerging market presence.
      • Others: Developing market for niche therapies.
    • By End User
      • Hospitals: High revenue from extensive therapy use.
      • Cancer Treatment Centers: Increasing volume as centers specialize in ALL.
    • By Geography
      • North America: Leading market with significant adoption.
      • Europe: Growing market with strong performance.
      • Asia-Pacific: Increasing market share with rising adoption.
      • Latin America: Developing market with gradual growth.
      • The Middle East and Africa: Limited market presence with potential for expansion.
  • Chronic Lymphocytic Leukemia (CLL)
    • By Drug Type
      • Axicabtagene Ciloleucel: Limited market share; developing applications.
      • Tisagenlecleucel: Moderate market presence.
      • Brexucabtagene Autoleucel: Developing presence.
      • Others: Niche market with growing potential.
    • By End User
      • Hospitals: Revenue generation from specialized treatments.
      • Cancer Treatment Centers: Increasing volume due to specialized focus.
    • By Geography
      • North America: Emerging market with growing adoption.
      • Europe: Developing market with expanding usage.
      • Asia-Pacific: Increasing market presence.
      • Latin America: Small market with potential growth.
      • The Middle East and Africa: Limited but growing market.
  • Multiple Myeloma (MM)
    • By Drug Type
      • Axicabtagene Ciloleucel: Emerging market with growing revenue.
      • Tisagenlecleucel: Increasing market presence.
      • Brexucabtagene Autoleucel: Developing market.
      • Others: Growing market with emerging therapies.
    • By End User
      • Hospitals: Significant revenue from therapy administration.
      • Cancer Treatment Centers: Growing volume as specialized centers adopt therapy.
    • By Geography
      • North America: Leading market with high adoption.
      • Europe: Growing market with increasing adoption.
      • Asia-Pacific: Emerging market with rising potential.
      • Latin America: Developing market with gradual growth.
      • The Middle East and Africa: Limited market presence with potential for expansion.
  • Others
    • By Drug Type
      • Axicabtagene Ciloleucel: Niche market presence for other indications.
      • Tisagenlecleucel: Developing presence in less common indications.
      • Brexucabtagene Autoleucel: Emerging market for niche applications.
      • Others: Various therapies with growing market segments.
    • By End User
      • Hospitals: Revenue generation from various therapies.
      • Cancer Treatment Centers: Increasing volume as specialized therapies become available.
    • By Geography
      • North America: Developing market with high adoption rates.
      • Europe: Growing market with emerging indications.
      • Asia-Pacific: Rising market presence with increasing adoption.
      • Latin America: Small but expanding market.
      • The Middle East and Africa: Limited market presence with potential growth.

By End User

  • Hospitals
    • By Drug Type
      • Axicabtagene Ciloleucel: High revenue due to high-cost therapy administration.
      • Tisagenlecleucel: Significant volume and revenue.
      • Brexucabtagene Autoleucel: Growing revenue as adoption increases.
      • Others: Smaller but developing revenue streams.
    • By Indication
      • Lymphoma: High market value and volume.
      • Acute Lymphocytic Leukemia (ALL): Significant therapy use.
      • Chronic Lymphocytic Leukemia (CLL): Moderate market presence.
      • Multiple Myeloma (MM): Growing market value.
      • Others: Niche indications with developing market.
    • By Geography
      • North America: Leading market with high adoption and revenue.
      • Europe: Growing market with significant revenue.
      • Asia-Pacific: Increasing market presence with rising adoption.
      • Latin America: Developing market with potential growth.
      • The Middle East and Africa: Limited presence but expanding opportunities.
  • Cancer Treatment Centers
    • By Drug Type
      • Axicabtagene Ciloleucel: Growing volume and revenue.
      • Tisagenlecleucel: Significant market presence.
      • Brexucabtagene Autoleucel: Emerging market with increasing adoption.
      • Others: Developing presence for niche therapies.
    • By Indication
      • Lymphoma: High volume and revenue.
      • Acute Lymphocytic Leukemia (ALL): Increasing adoption and volume.
      • Chronic Lymphocytic Leukemia (CLL): Developing market presence.
      • Multiple Myeloma (MM): Growing indication with increasing volume.
      • Others: Niche applications with expanding market.
    • By Geography
      • North America: Leading market with high adoption and revenue.
      • Europe: Growing presence with increasing volume.
      • Asia-Pacific: Emerging market with rising adoption.
      • Latin America: Developing market with gradual growth.
      • The Middle East and Africa: Limited presence with potential for expansion.

By Geography

  • North America
    • By Drug Type
      • Axicabtagene Ciloleucel: Dominant market with high revenue and volume.
      • Tisagenlecleucel: Significant market share.
      • Brexucabtagene Autoleucel: Emerging market presence.
      • Others: Developing market for niche therapies.
    • By Indication
      • Lymphoma: Highest market value and volume.
      • Acute Lymphocytic Leukemia (ALL): Significant adoption.
      • Chronic Lymphocytic Leukemia (CLL): Growing market.
      • Multiple Myeloma (MM): Increasing presence.
      • Others: Various indications with emerging market potential.
    • By End User
      • Hospitals: Major revenue and volume.
      • Cancer Treatment Centers: Growing market presence.
  • Europe
    • By Drug Type
      • Axicabtagene Ciloleucel: Significant market presence with growing adoption.
      • Tisagenlecleucel: Increasing market value and volume.
      • Brexucabtagene Autoleucel: Developing presence.
      • Others: Smaller market for niche therapies.
    • By Indication
      • Lymphoma: High market presence.
      • Acute Lymphocytic Leukemia (ALL): Growing market.
      • Chronic Lymphocytic Leukemia (CLL): Emerging market.
      • Multiple Myeloma (MM): Increasing market value.
      • Others: Various indications with developing presence.
    • By End User
      • Hospitals: Significant market presence.
      • Cancer Treatment Centers: Growing volume and revenue.
  • Asia-Pacific
    • By Drug Type
      • Axicabtagene Ciloleucel: Emerging market with increasing adoption.
      • Tisagenlecleucel: Growing market presence.
      • Brexucabtagene Autoleucel: Developing presence.
      • Others: Niche therapies with growing market.
    • By Indication
      • Lymphoma: Increasing market share.
      • Acute Lymphocytic Leukemia (ALL): Emerging presence.
      • Chronic Lymphocytic Leukemia (CLL): Growing market value.
      • Multiple Myeloma (MM): Developing market.
      • Others: Various indications with emerging presence.
    • By End User
      • Hospitals: Growing revenue and volume.
      • Cancer Treatment Centers: Increasing adoption.
  • Latin America
    • By Drug Type
      • Axicabtagene Ciloleucel: Developing market presence.
      • Tisagenlecleucel: Growing adoption.
      • Brexucabtagene Autoleucel: Emerging market.
      • Others: Niche therapies with gradual growth.
    • By Indication
      • Lymphoma: Increasing market presence.
      • Acute Lymphocytic Leukemia (ALL): Growing market value.
      • Chronic Lymphocytic Leukemia (CLL): Developing presence.
      • Multiple Myeloma (MM): Emerging market.
      • Others: Various indications with potential growth.
    • By End User
      • Hospitals: Developing market with growing adoption.
      • Cancer Treatment Centers: Increasing volume and revenue.
  • The Middle East and Africa
    • By Drug Type
      • Axicabtagene Ciloleucel: Limited presence with potential for growth.
      • Tisagenlecleucel: Growing market.
      • Brexucabtagene Autoleucel: Emerging presence.
      • Others: Developing niche therapies.
    • By Indication
      • Lymphoma: Expanding market presence.
      • Acute Lymphocytic Leukemia (ALL): Increasing adoption.
      • Chronic Lymphocytic Leukemia (CLL): Developing market.
      • Multiple Myeloma (MM): Growing presence.
      • Others: Niche indications with expanding market.
    • By End User
      • Hospitals: Limited presence with potential growth.
      • Cancer Treatment Centers: Emerging market with growing volume.

Competitive Landscape

  • Market Share Analysis
  • Company Profiles
  • Key Players
    • Johnson & Johnson Services, Inc.
    • ALLOGENE THERAPEUTICS
    • Lonza
    • Aurora Biopharma
    • Cartesian Therapeutics, Inc.
    • Novartis
    • Bristol-Myers Squibb company
    • Gilead Sciences
    • Curocell Inc
    • JW Therapeutics
    • Other Key Players
  • Competitive Strategies
    • Product Launches
    • Mergers and Acquisitions
    • Partnerships and Collaborations
  • Recent Developments

Regulatory Landscape

  • Regulatory Approvals
  • Market Authorization Processes
  • Current Guidelines and Standards
  • Technological Advancements
  • Innovations in Therapy Development
  • Patient and Physician Perspectives

Investment Analysis

  • Funding and Investments
  • Venture Capital and Private Equity
  • Market Entry Strategies

Future Outlook

  • Market Opportunities
  • Emerging Trends
  • Forecast and Predictions

Appendix

  • Data Sources
  • Glossary of Terms
  • List of Abbreviations
  • Contact Information

FAQ's

Answer : The CAR T-cell therapy market, valued at USD 12.88 billion in 2025 and USD 16.23 billion in 2026, is projected to soar to USD 193.6 billion by 2035 at a CAGR of 29.80%.

Answer : North America currently leads due to advanced infrastructure and high adoption rates, while Asia-Pacific is the fastest-growing region driven by government initiatives, investments, and rising clinical trials.

Answer : Lymphoma leads in market share due to high prevalence and unmet treatment needs, whereas acute lymphocytic leukemia is the fastest-growing segment owing to increased incidence rates.

Answer : Hospitals hold the largest market share due to infrastructure and reimbursement support, while cancer treatment centers are expanding fastest with specialized CAR T capabilities.

Answer : AI enhances CAR T-cell design, personalizes treatment, streamlines manufacturing, predicts patient responses, and improves monitoring through smart devices and real-time analytics.

Meet the Team

Rohan Patil is a seasoned market research professional with over 5+ years of focused experience in the healthcare sector, bringing deep domain expertise, strategic foresight, and analytical precision to every project he undertakes.

Learn more about Rohan Patil

Aditi Shivarkar is a seasoned professional with over 14 years of experience in healthcare market research. As a content reviewer, Aditi ensures the quality and accuracy of all market insights and data presented by the research team.

Learn more about Aditi Shivarkar