The U.S. home infusion therapy market size accounted for USD 15.1 billion in 2025 and is predicted to increase from USD 16.2 billion in 2026 to approximately USD 30.55 billion by 2035, expanding at a CAGR of 7.30% from 2026 to 2035. Home infusion therapy has increased significantly due to the targeted, suitable, and high-quality care it provides, which drives the growth of the market.
Home infusion includes the administration of a medication via a catheter in a setting other than a hospital or a healthcare facility. Patients who require infusion therapy are maintained by pharmacists, nurses, and other professionals with special training in offering infusion medications. Infusing medicines at home or elsewhere outside of an institutional setting lowers time spent away from normal activities, like school, work, and hobbies, while completing therapy. Home infusion is an effective and safe alternative to inpatient care for a diversity of therapies and disease states, both acute and chronic. Home infusion therapy is used for various conditions, including infections such as sepsis, pneumonia, or endocarditis, which require IV antibiotics, antifungals, or antivirals.
More than 60% of drugs currently in development are infusion-delivered therapies.
Technological advancements have broadened and improved the effectiveness of home infusion therapy. Cancer patients also receive treatments such as antimicrobial therapy, chemotherapy, pain management, total parenteral nutrition, and blood transfusions at home. The incorporation of digital devices marks an important step forward in patient-centered care and allows for more targeted treatment experiences tailored to individual requirements. This shift aims to increase health results and overall quality of life. The increasing popularity of digital engagement tools highlights a wider trend towards real-time, interactive communication among patients and healthcare providers.
By product, the infusion pumps segment contributed the largest U.S. home infusion therapy market share of 41% in 2025, as infusion pumps offer the benefits of controlled administration, the capability to deliver fluids in small volumes or at exactly programmed rates or intervals. Many novel infusion pumps are furnished with predetermined clinical strategies, dose error reduction systems (DERSs), and drug libraries which offers a inclusive list of therapeutics and fluids.
By therapy type, the anti-infective infusion therapy segment contributed the largest market share of 26%, as anti-infective therapy provides specialized infusions and specialty therapeutics designed to supports to manage complex viral, bacterial, and fungal infections. It supports reducing the requirement for prolonged hospital stays.
By route of administration, the intravenous segment held a significant share of 63% in the U.S. home infusion therapy market, as intravenous (IV) therapy is the administration of fluids directly into a patient's vein. It works more rapidly than an oral route, allowing medication, water, blood, and nutrients to shift via the circulatory system rapidly and target the tissue or organ that requires them.
By end user, the hospitals segment contributed the largest market share of 36%, as in hospitals, IV therapies are specially formulated liquids that are injected into a vein to avoid or manage dehydration. IV infusion therapy delivers fluids, blood, nutrients, and medication directly to the bloodstream to supports to feel better rapidly.
By provider type, the hospital-based infusion providers segment held a significant share of 39% in the U.S. home infusion therapy market, as hospital-based infusion providers offer supreme safety, inclusive medical oversight, and multidisciplinary direction, creating them ideal for patients with severe health conditions. Hospital-driven services are typically covered under standard hospital-facility fees.
The four organizations in this market dominate the U.S. Home Infusion Therapy Market. Meanwhile, Option Care Health, it provides clinical management and a comprehensive infusion solution. Coram CVS Health is offering a home and alternate-site infusion solution for thousands of patients worldwide. Optum Infusion Services, significant integrated pharmacy and infusion care provider that serves patients. KabaFusion is heavily focused on IV immune globulin (IVIG) therapies, anti-infectives, and nutrition support.
By Product
By Therapy Type
By Route of Administration
By Applications
By End User
By Provider Type
