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The Arima Genomics, Inc., a leading structure information and whole-genome sequence-focused company serving robust cancer therapy selection insights, has declared its new study led by an investigator group at Johns Hopkins University, highlighting the aventa lymphoma test turned vague FISH (fluorescent in situ hybridisation) results into a precise clinical proven answer for diffuse large B-cell lymphoma (DLBCL) patients. The accurate and fragile test, mainly for gene reposition and blend, is fundamental to ensure a precise lymphoma diagnosis.
The FISH is used across probe-related test that depends on interrogation and microscopy with a single preselected focus, one at a time. Whereas, aventa lymphoma accelerates genome-wide Hi-C sequencing to examine all similar repositioning and blend in one assay.
The new study published in a healthcare market in a valuable issue of the colleague-reviewed scientific journal ‘Genes’ is connected to ‘cytogenetics and cytogenomics in clinical diagnostics: innovations and applications’. This entitled journal targets on a series of diagnostically burdened cases incorporated into FISH findings. The aventa lymphoma test has validated and green signalled all typical FISH results with clarity in results, confirming the FISH patterns will not be titled to full clinical interpretation and characterisation, as it's still ambiguous.
The aventa lymphoma unlocked integration of clinically consequential repositioning that were not focused on by FISH testing in all means as found. This moves diagnoses, aims clinicians and refines prognoses to focus clinical trials or regimens. Further, the study details case findings, alterations and effects on the patients. Also, it showed aventa lymphoma’s side of vastness and an unbiased viewpoint serving essential information that might trim treatment.
The MD, PhD, Director of cancer cytogenetic laboratory, cytogenomic research core and associate director of molecular diagnostics laboratory at Johns Hopkins University and a senior author of the study, Ying Zou, said, “In DLBCL, we most probably follow patterns that FISH cannot explain independently. In this new study, aventa lymphoma served as the lost context from its regular FFPE tissue. This grounds co-alterations and gives clear insight into diagnoses that, in a way, convey potential and risk treatment paths.”
The PhD, senior vice president, science at Arima Genomics, Anthony Schmitt, said, “This study marks our clarification of unclear FISH cases and has revealed the hidden variants that will support clinicians in measuring risk and introduce patients to accurate trials and therapies. Our specific goal is to achieve clarification regularly in lymphoma care.”
Mansi Kadam is a market research writer with over 3 years of experience analyzing trends in the healthcare industry. At Towards Healthcare, she covers innovations in medical sector, sustainability initiatives, and the evolving regulatory landscape.
