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Non-small Cell Lung Cancer Therapeutics Market Soars 12.74% CAGR by 2034

Non-small Cell Lung Cancer Therapeutics Market Innovations & Dynamics

Market insights predict, the non-small cell lung cancer therapeutics industry is expected to grow from USD 21.5 billion in 2024 to USD 71.2 billion by 2034, driven by a CAGR of 12.74%. The non-small cell lung cancer therapeutics market is expanding due to the rising occurrence of non-small cell lung cancer as well as growing targeted treatment approaches. North America led the market due to the presence of advanced industries.

Category: Therapeutic Area Insight Code: 5668 Format: PDF / PPT / Excel

Kesiya Chacko

Principal Consultant

Aditi Shivarkar

Reviewed By

Non-small Cell Lung Cancer Therapeutics Market Size and Competitive Landscape

The global non-small cell lung cancer therapeutics market size is calculated at USD 21.5 in 2024, grew to USD 24.24 billion in 2025, and is projected to reach around USD 71.2 billion by 2034. The market is expanding at a CAGR of 12.74% between 2025 and 2034.

Non-small Cell Lung Cancer Therapeutics Market Size 2024 - 2034

Key Takeaways

  • Non-small cell lung cancer therapeutics industry poised to reach USD 21.5 billion in 2024.
  • Forecasted to grow to USD 71.2 billion by 2034.
  • Expected to maintain a CAGR of 12.74% from 2025 to 2034.
  • North America dominated the global non-small cell lung cancer therapeutics market share by 36% in 2024.
  • Asia Pacific is expected to be the fastest-growing during the forecast period.
  • By type, the adenocarcinoma segment dominated the market in 2024.
  • By type, the squamous cell carcinoma (SCC) segment is expected to be the fastest growing at a notable CAGR during the forecast period.
  • By treatment type, the targeted therapy segment dominated the market in 2024.
  • By treatment type, the immunotherapy segment is expected to grow significantly during the forecast period.
  • By distribution channel type, the hospital segment dominated the global non-small cell lung cancer therapeutics market in 2024.
  • By distribution channel type, the drug store and retail pharmacy segment is expected to grow significantly during the forecast period.

Key Metrics and Overview

Metric Details
Market Size in 2025 USD 24.24 Billion
Projected Market Size in 2034 USD 71.2 Billion
CAGR (2025 - 2034) 12.74%
Leading Region North America share by 36%
Market Segmentation By Type, By Treatment, By Distribution Channel, By Region
Top Key Players Merck & Co., Inc., Teva Pharmaceutical Industries Ltd., F. Hoffmann-La Roche Ltd., Sanofi, Mylan N.V., Bayer AG, Novartis AG, Pfizer Inc., GSK plc, Eli Lilly and Company

Market Overview

Non-small cell lung cancer (NSCLC) consists of various risk factors such as smoking, genetic, as well as environmental factors. The treatment options provided to the patients depend on the stages of the cancer. Nowadays, the effective management of lung cancer is done with the help of targeted therapy and immunotherapy. At the same time, personalized approaches are also provided by biomarker or genetic testing. These offer enhanced precision by targeting specific mutations. Furthermore, vaccines are also being investigated as the next treatment approach for NSCLC.

  • In May 2025, a collaboration between AbbVie and ADARx Pharmaceuticals for developing novel siRNA therapeutics was announced. The EMRELIS, which is a treatment for non-small cell lung cancer, developed by this collaboration, recently received accelerated FDA approval. (Source - finance)
  • In May 2025, a licence for developing, manufacturing, and commercializing SSGJ-707 was granted to Pfizer as per the agreement by 3SBio and its subsidiaries, Shenyang Sunshine Pharmaceutical and 3S Guojian Pharmaceutical, which is considered to be a deal worth $6bn. The SSGJ-707 is being evaluated for the treatment of non-small cell lung cancer, gynaecological tumours, and metastatic colorectal cancer. (Source - PMLIVE)

AI Integration in the Non-Small Cell Lung Cancer Therapeutics Market

There are various applications of AI in lung cancer research. It can be used in domains such as pathomics, genomics, radiomics, transcriptomics, microbiomics, proteomics, immunomics, and metabolomics. At the same time, it can be used in drug discovery, early diagnosis, formulating personalized treatment approaches, and monitoring. Furthermore, it also helps in anticipating responses to the immunotherapies as well as survival rates. Thus, AI plays a crucial role in combating NSCLC, which in turn helps in enhancing patient outcomes as well as quality of life.

Market Dynamics

Driver

Increasing Occurrence of Non-Small Cell Lung Cancer

There is a rise in the occurrence of non-small cell lung cancer, due to which there is an increase in the demand for new diagnostic as well as treatment approaches. At the same time, various awareness programs are being conducted, which increases the demand as well as the use of early diagnosis. This, in turn, contributes to the growing use of various treatment approaches. Furthermore, new personalized treatment options are also increasing. Thus, all the factors drive the non-small cell lung cancer therapeutics market growth.

Estimated Rates of Lung Cancer in U.S. in 2025

The graph represents the estimated rates of lung cancer in the U.S. for 2025. It indicates that there will be a rise in cases of lung cancer. Hence, it increases the demand for new therapeutic options for the effective management of lung cancer. Thus, this in turn will ultimately promote the market growth.

Restraint

Side Effects

The treatment options used for non-small cell lung cancer may have various side effects. These side effects may affect the immune system or even the liver, due to which these treatments may be discontinued. At the same time, nausea or fatigue also reduces the acceptance rate of these treatments, resulting in a restraint on the market growth.

Opportunity

Rising Targeted Treatment Approaches

Due to the increase in non-small cell lung cancer cases, as well as due to side effects associated with certain medications, the demand for targeted and personalized treatment options is rising. This, in turn, increases the research and development focusing on these approaches. Furthermore, this also results in their increased acceptance rates. Thus, new targeted drugs or therapies with enhanced safety and efficacy are being developed along with personalized medications. This, in turn, helps in minimizing the side effects, which helps in improving patient outcomes. Thus, all these factors promote the non-small cell lung cancer therapeutics market growth.

For instance,

  • In April 2025, a clinical trial conducted for zoldonrasib, which is a drug targeting the KRAS G12D mutation seen in non-small cell lung cancer, developed by Revolution Medicines, showed shrinking of tumors in approximately 60% of patients. (Source - PRECISION MEDICAL ONLINE)

Segmental Insights

Why Adenocarcinoma Segment Dominated in 2024?

By type, the adenocarcinoma segment dominated the market in 2024. The increased cases, along with rising mutations in adenocarcinoma, contributed to the increased use of therapeutics. This enhanced the non-small cell lung cancer therapeutics market growth.

By type, the squamous cell carcinoma (SCC) segment is estimated to be the fastest growing at a notable CAGR during the forecast period. The squamous cell carcinoma incidence is rising, as well as the growing awareness about early diagnosis is also increasing the use of therapeutics for its effective management.

Why was the Targeted Therapy Segment Dominant in 2024?

By treatment type, the targeted therapy segment dominated the market in 2024. The targeted therapy provided a reduction in the genetic mutations due to its target-specific action, which in turn, enhanced the patient outcomes as well as market growth.

By treatment type, the immunotherapy segment is anticipated to grow significantly during the forecast period. The use of immunotherapies is increasing as they can be used in the early stages of NSCLC as well as in combination with targeted therapies or chemotherapy, which helps in enhancing the effectiveness of the treatment.

What Made the Hospital Segment Lead in 2024?

By distribution channel type, the hospital segment dominated the global non-small cell lung cancer therapeutics market in 2024. Hospitals provided various services from diagnosis to treatment. At the same time, the advanced treatment approaches with specialized personnel helped in the management of NSCLC cases.

By distribution channel type, the drug store and retail pharmacy segment is predicted to grow significantly during the forecast period. The drug store and retail pharmacy are providing various medications to the NSCLC patients with enhanced accessibility. This, in turn, promotes the market growth.

How are Different Regions Contributing to the Non-Small Cell Lung Cancer Therapeutics Market Growth?

Non-small Cell Lung Cancer Therapeutics Market Share, By Region, 2024 (%)

Advanced Industries Drive North America

North America dominated the non-small cell lung cancer therapeutics market share by 36% in 2024. North America consisted of well-established industries along with new technologies, as well as skilled personnel. This increased the development as well as production of various non-small cell lung cancer therapeutics, contributing to the market growth.

The U.S. Non-Small Cell Lung Cancer Therapeutics Market Trends

The industries in the U.S. are well-developed, due to which the development of new therapeutics is rising. At the same time, they also enhance the production rate with the use of advanced technologies, by maintaining their quality and safety with the help of skilled personnel.

The Canada Non-Small Cell Lung Cancer Therapeutics Market Trends

Due to increasing interest in the development of new personalized and targeted therapeutics, the industries in Canada are focusing on the research and development of the same. This increases the collaboration between the companies.

Increasing Lung Cancer Boosts Asia Pacific

Asia Pacific is estimated to host the fastest-growing non-small cell lung cancer therapeutics market during the forecast period. Asia Pacific is experiencing a rise in the incidence of lung cancers. This, in turn, increases the demand for various therapeutics. Thus, this enhances the market growth.

The China Non-Small Cell Lung Cancer Therapeutics Market Trends

The healthcare sector in China is adopting various advanced technologies to deal with the increasing occurrences of lung cancer. These technologies are being utilized to enhance the development and reduce the errors associated with the development of therapeutics.

The India Non-Small Cell Lung Cancer Therapeutics Market Trends

The rising incidence of lung cancer in India is increasing the demand as well as the development of new therapeutics. At the same time, to make these advancements affordable government is also providing its support.

Europe Driven by Personalized Treatments

Europe is expected to grow significantly in the non-small cell lung cancer therapeutics market during the forecast period. With the increasing prevalence as well as awareness in Europe, the demand for the use of personalized treatment options is growing. This promotes the market growth.

The Germany Non-Small Cell Lung Cancer Therapeutics Market Trends

The production, as well as research and development for personalized treatment options, is increasing in Germany. This is due to growing incidences of non-small cell lung cancer cases. Thus, these developments are supported by the funding provided by the government.

The UK Non-Small Cell Lung Cancer Therapeutics Market Trends

The increasing awareness within the population is increasing the demand as well as the use of personalized treatment approaches. At the same time, new such medications are being developed, increasing the clinical trials supported by the regulatory bodies.

Top Companies in the Non-Small Cell Lung Cancer Therapeutics Market

Non-Small Cell Lung Cancer Therapeutics Market Companies

Latest Announcements by Industry Leaders

  • In May 2025, a thoracic medical oncologist and early drug development specialist, M.D. Helena Yu, from Memorial Sloan Kettering Cancer Center, stated that the need for well-tolerated targeted therapies, along with durable clinical benefit, is increasing for people with EGFR ex20ins NSCLC. She further stated that, with the help of the program, a potential option for the sickest patients with lung cancer will be offered. Furthermore, the patient in whom the disease progressed despite the prior treatment, the findings of the REZILIENT1 trial may support that zipaltinib can be used as an oral treatment option. (Source - ENZENE)
  • In May 2025, after the approval of VENTANA MET, the CEO of Roche Diagnostics, Matt Sause, stated that, for therapy selection, it is crucial to understand the molecular drivers in NSCLC patients. Thus, with the help of VENTANA MET, the patient outcomes can be enhanced, as well as it can provide a hope for serious patients, by identifying MET protein expression at the appropriate stage, which can be used in formulating tailored treatment options. (Source - Medical dialogues)

What are the Latest Developments in the Non-Small Cell Lung Cancer Therapeutics Market?

  • In May 2025, a 60.8% response rate and 90.2% disease control rate were observed by the INSIGHT-003 trial, which was developed by Immutep Limited, as per the RECIST1.1. This trial is for evaluating the first-line treatment option for patients with metastatic and advanced non-squamous non-small cell lung cancer (1L NSCLC), which includes a combination of eftilagimod alpha (efti), anti-PD-1 therapy, KEYTRUDA® (pembrolizumab), and doublet chemotherapy. (Source - THE MANALI TIMES)
  • In April 2025, PD-1xVEGF bispecific antibody ivonescimab, developed by Akeso and Summit Therapeutics, for advanced squamous non-small cell lung cancer (NSCLC), was successful in completing its phase 3 trials. (Source - FIERCE)

Segments Covered in the Report

By Type

  • Squamous Cell Carcinoma
  • Large Cell Carcinoma
  • Adenocarcinoma
  • Others

By Treatment

  • Chemotherapy
  • Targeted Therapy
  • Immunotherapy
  • Others

By Distribution Channel

  • Hospital Pharmacy
  • Drug Store and Retail Pharmacy
  • Online Pharmacy

By Region

  • North America
    • U.S.
    • Canada
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Thailand
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Sweden
    • Denmark
    • Norway
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East and Africa (MEA)
    • South Africa
    • UAE
    • Saudi Arabia
    • Kuwait
  • Last Updated: 02 June 2025
  • Report Covered: [Revenue + Volume]
  • Historical Year: 2021-2023
  • Base Year: 2024
  • Estimated Years: 2025-2034

Meet the Team

Kesiya Chacko is an accomplished market research professional with over 4+ years of experience in the healthcare industry, known for delivering actionable insights and strategic analysis that empower healthcare organizations.

Learn more about Kesiya Chacko

Aditi Shivarkar, with over 14 years of experience in consumer goods, leads research at Towards Consumer Goods, ensuring precise, actionable insights on trends, consumer preferences, and sustainable packaging for businesses.

Learn more about Aditi Shivarkar

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FAQ's

A non-small cell lung cancer is a type of carcinoma, which may be adenocarcinoma or squamous cell carcinoma of the lungs and does not include small cell carcinoma.

Merck & Co., Inc. is the major player in the market.

American Cancer Society, Ministry of Health and Family Welfare, Government of India, National Institutes of Health, FDA, WHO, PIB, CDC.