Chemical/Gas Sterilizers Market Trends Shaping Global Demand

Revenue, 2025

USD 1.55 Billion

Forecast, 2035

USD 2.47 Billion

CAGR, 2026-2035

4.76%

Report Coverage

Global

Chemical/Gas Sterilizers Market Size, Dynamics with Insights and Key Players

The global chemical/gas sterilizers market size was estimated at USD 1.55 billion in 2025 and is predicted to increase from USD 1.62 billion in 2026 to approximately USD 2.47 billion by 2035, expanding at a CAGR of 4.76% from 2026 to 2035.

The growing disease burden and surgical procedures globally are increasing the demand for chemical/gas sterilizers, where AI technologies are being used to enhance their optimization and ensure effectiveness and safety. Expanding healthcare, advanced hospitals, and stringent regulations are also encouraging their use. At the same time, the companies are also investing and launching new chemical/gas sterilizer products, which is promoting the market growth.

Key Takeaways

• Chemical/gas sterilizers industry poised to reach USD 1.62 billion by 2026.
• Forecasted to grow to USD 2.47 billion by 2035.
• Expected to maintain a CAGR of 4.76% from 2026 to 2035.
• North America held the major revenue share in the global chemical/gas sterilizers market in 2025.
• Asia Pacific is expected to be the fastest-growing region between 2026 and 2035.
• By product type, the hydrogen peroxide sterilization segment dominated the market in 2025.
• By product type, the ethylene oxide sterilization segment is expected to be the fastest growing during the forecast period.
• By end user, the hospital & specialty clinics segment dominated the market in 2025.
• By end user, the pharmaceutical & medical device manufacturers segment is expected to be the fastest growing during the forecast period.

Quick Facts Table

What are the Chemical/Gas Sterilizers?

The chemical/gas sterilizers market is driven by the rising volume of surgical procedures and the global burden of hospital-acquired infections (HAIs). The chemical/gas sterilizers refer to the products that utilize chemical agents and sterilizing gases for eliminating all forms of microorganisms present on the laboratory equipment and medical, industrial. They are being used to sterilize heat-sensitive medical instruments, packed items, laboratory equipment, and infection control.

What is the Use of AI in the Chemical/Gas Sterilizers Market?

The use of AI in the optimization of the chemical/gas sterilizer is increasing, where they analyze the sterilization cycle and adjust parameters to offer fast and effective sterilization. It also helps in detecting the sterilizers' leaks and unusual chemical usage and automatically adjusts the process, reducing their degradation and ensuring safety. It is also used for quality control and monitoring the effectiveness of the sterilization.

What are the Trends & Future Outlook of the Chemical/Gas Sterilizers Market?

Expanding Healthcare

The hospital, clinics, and surgical centres globally are increasing, which is driving the demand for chemical/gas sterilizers, especially during surgical procedures and instrument sterilization.

Focus on Safety and Infection Control

The growing focus on infection control is increasing the use of chemical/gas sterilization, which in turn is also driving the development of eco-friendly and safer sterilizers.

Rising Innovations

The companies are using various sterilization systems for faster sterilization and lower residues, where they are also utilizing advanced technologies for their automated sterilizations.

Major Investments in the Chemical/Gas Sterilizers Market

• In September 2025, a total of $30 million in growth capital was received by Noxilizer, Inc., where the capital will be utilized to expand its infrastructure and access to its nitrogen dioxide (NO₂) terminal sterilization technology.
• In February 2025, a successful commission of Rs 11.7 billion was secured by Engro Polymer & Chemicals (EPCL) for its hydrogen peroxide plant, where the investment from the International Finance Corporation (IFC) will also promote its expansion.

Segmental Insights

By Product Type Insights

Which Product Type Segment Held the Dominating Share of the Chemical/Gas Sterilizers Market in 2025?

The hydrogen peroxide sterilization segment held the dominating share in the market in 2025, due to its broad-spectrum efficacy. At the same time, they were used in the sterilization of heat-sensitive medical devices, where their material compatibility also increased the acceptance rates. Additionally, no toxic residues and faster sterilization cycles also increased their use.

Ethylene Oxide Sterilization

The ethylene oxide sterilization segment is expected to show the fastest growth rate during the predicted time, due to its high penetration ability. This is increasing their use for complex and multi-layered medical devices, along with temperature-sensitive products. Furthermore, their high scalability is also increasing their use for the sterilization of implants.

By End User Insights

What Made Hospital & Specialty Clinics the Dominant Segment in the Chemical/Gas Sterilizers Market in 2025?

The hospital & specialty clinics segment led the market in 2025, due to frequent use of surgical instruments, which increased the demand for chemical/gas sterilizers. At the same time, stringent infection control and growth in the patient volume also increased their use for the sterilization of various equipment and devices.

Pharmaceutical & Medical Device Manufacturers

The pharmaceutical & medical device manufacturers segment is expected to show the highest growth during the upcoming years, due to stringent sterility standards, which increased the use of chemical/gas sterilizers. Moreover, the growth in single-use medical devices, implants, and advanced therapies is also increasing their use. Additionally, the growth in the manufacturing and R&D activities is also increasing the demand.

Regional Distribution

• North America held the dominance in the market in 2025.
• The U.S. led the market by capturing the largest revenue share of the market in 2025. 
• Asia Pacific is expected to be a significantly growing region in the studied years.
• India is anticipated to grow at a rapid CAGR during the forecast period.
• Europe is expected to grow at a notable CAGR in the chemical/gas sterilizers market during the forecast period.
• The UK is anticipated to grow at a rapid CAGR during the forecast period. 

Why Does Advanced Healthcare Drive North America?

North America dominated the chemical/gas sterilizers market in 2025, due to the presence of advanced healthcare infrastructure, as they were used for infection control. At the same time, the growth in the surgical procedures and stringent regulations also increased their use. Furthermore, the industries also utilized them due to the growth in medical devices, which contributed to the market growth.

The presence of well-developed hospitals, surgical centers, and clinics across the U.S. is increasing the use of chemical/gas sterilizers. The growing number of surgeries and complex diseases is increasing their demand, where the growing development of medical devices and advanced sterilization technologies is also increasing their use.

Does Expanding Healthcare Boost the Asia Pacific?

Asia Pacific is expected to host the fastest-growing chemical/gas sterilizers market during the forecast period, due to expanding healthcare, where the growing surgical procedures and chronic diseases are also increasing their use. The growing development of advanced therapies and medical devices is also increasing their use, where the demand for low-temperature sterilization is also enhancing the market growth.

India is experiencing a rapid healthcare expansion, which is increasing the demand for chemical/gas sterilizers. At the same time, the growing diseases and surgical volumes are also increasing their use, where rising infection control measures are also increasing their demand. Furthermore, the growing innovation and government initiatives are also increasing their use.

What Factor Propels Europe?

Europe is expected to grow significantly in the chemical/gas sterilizers market during the forecast period, due to stringent regulatory standards. This is increasing the use of chemical/gas sterilizers across the advanced healthcare system, where the focus on patient safety is also increasing their demand. Additionally, the growing innovations and diseases are also promoting the market growth.

The UK consists of well-established healthcare systems that utilize chemical/gas sterilizers to ensure sterility and regulatory compliance. They are also focusing on infection control, where the growing advanced therapies are also increasing their use. Furthermore, the companies are also developing eco-friendly sterilizers along with technological advancements.

Chemical/Gas Sterilizers Market Value Chain Analysis

R&D

• The R&D of the chemical/gas sterilizers focuses on the development of sustainable, low-temperature alternatives and integration of AI for cycle optimization, and IoT-enabled remote monitoring.
• Key players: STERIS, Getinge AB, Noxilizer, Inc.

Clinical Trials and Regulatory Approvals

• Medical device compatibility, compliance with new 21 CFR Part 213 for medical gases, and performance validation are involved in the clinical trials and regulatory approval of the chemical/gas sterilizers.
• Key players: STERIS, Getinge AB, Advanced Sterilization Products (ASP).

Formulation and Final Dosage Preparation

• The formulation and final dosage preparation of the chemical/gas sterilizers include the highly purified agents delivered on precision-controlled formats to ensure consistent microbial elimination with reduced residual toxicity.
• Key players: STERIS, Noxilizer, Inc., Advanced Sterilization Products (ASP)

Packaging and Serialization

• The packaging and sterilization of the chemical/gas sterilizers consist of breathable, medical-grade materials with integration with 2D data matrices and IoT-enabled software to ensure full 21 CFR Part 11 compliance traceability.
• Key players: STERIS, Advanced Sterilization Products (ASP).

Distribution to Hospitals, Pharmacies

• Integrated global logistic networks, decentralized hubs managed by manufacturers, and major medical distributors help in the distribution of chemical/gas sterilizers to hospitals and pharmacies.
• Key players: STERIS, Getinge AB, Cardinal Health.

Patient Support and Services

• Procedure safety, educational programs, technical support, and remote monitoring services are provided in the patient support and services of the chemical/gas sterilizers.
• Key players: STERIS, Getinge AB, Advanced Sterilization Products (ASP).

Who are the Top Vendors in the Chemical/Gas Sterilizers Market and What are Their Offerings?

SWOT Analysis

Strengths

• Their effectiveness for heat-sensitive products, such as plastics, flexible endoscopes, etc., is increasing their adoption rates.
• They also ensure complete sterilization as they offer high penetration power, which increases their use in the sterilization of complex lumens.
• Additionally, they are also being used in the stabilization of sensitive instruments as they provide low-temperature processing.
• Furthermore, the broad spectrum of action also increased their use for eliminating different types of bacteria, resistant spores, fungi, and viruses.

Weaknesses

• Lengthy process consisting of long sterilization and aeration cycles limits the use of chemical/gas sterilizers, which act as the major weakness in the chemical/gas sterilizers market.
• Limited material compatibility with products consisting of cellulose, certain plastics and metals, and liquids also reduces their use.

Opportunities

• The growth in the surgical volumes is driving the demand for chemical/gas sterilizers to reduce the risks of hospital-acquired infections and safety concerns.
• The industries are also utilizing these sterilizers for maintaining the sterility of various instruments, products, and devices.
• The growing number of surgical centres, along with stringent regulations, is increasing the use of these sterilizers.
• Additionally, the growing shift towards low-temperature sterilization is also driving their demand for various purposes.

Threats

• Safety concerns act as the major threat, as the chemical/gas sterilizers may lead to irritation as well as cancer among the manufacturers.
• Stringent regulations also limit their use due to a complex validation and certification process, where their failure can lead to their ban.

Recent Developments in the Chemical/Gas Sterilizers Market

• In October 2025, a low-emission ethylene oxide (EO) system approved by the U.S. FDA, EOGas 4PLUS, was launched by Andersen Sterilization, making it the first and only method for the sterilization of the ≤3530mm lumens.
• In December 2025, the development of a 400 TPD Chlor-alkali plant at Dahej manufacturing complex in Gujarat was announced by Indian Peroxide Ltd (IPL), which will support the company’s hydrogen peroxide manufacturing base expansion.

Segments Covered in the Report

By Product Type

• Nitrogen Dioxide Sterilizers
• Hydrogen Peroxide Sterilization
• Ethylene Oxide Sterilization
• Others

By End-user

• Hospital & Specialty Clinics
• Pharmaceutical & Medical Device Manufacturers
• Others

By Region

• North America
  • U.S.
  • Canada 
  • Mexico 
  • Rest of North America
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Europe 
  • Western Europe 
    • Germany 
    • Italy
    • France
    • Netherlands
    • Spain
    • Portugal 
    • Belgium
    • Ireland
    • UK 
    • Iceland 
    • Switzerland
    • Poland
    • Rest of Western Europe
  • Eastern Europe 
    • Austria
    • Russia & Belarus 
    • Türkiye
    • Albania 
    • Rest of Eastern Europe 
• Asia Pacific
  • China 
  • Taiwan
  • India 
  • Japan 
  • Australia and New Zealand
  • ASEAN Countries (Singapore, Malaysia)
  • South Korea 
  • Rest of APAC 
• MEA 
  • GCC Countries
    • Saudi Arabia 
    • United Arab Emirates (UAE)
    • Qatar 
    • Kuwait 
    • Oman 
    • Bahrain 
  • South Africa
  • Egypt 
  • Rest of MEA