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Chronic Lower Back Pain Market Size and Companies Report by 2033

Chronic Lower Back Pain Market Size Envisioned at USD 6.12 Billion by 2033

The report covers Chronic Lower Back Pain Market Manufacturers and Segments Outlook starting with drug classes such as Non-steroidal Anti-inflammatory Drugs, Antidepressants, Analgesics, Opioids and others. It examines administration routes including oral, topical and others. The report assesses distribution channels, highlighting the roles of hospital pharmacies and retail & online pharmacies. Geographically, the analysis spans North America, Europe, Asia Pacific, Latin America and the Middle East & Africa. The report offers the value (in USD Billion) for the above segments.

Chronic Lower Back Pain Market Size, Future Outlook and Overview Report

The chronic lower back pain market was valued at US$ 2.46 billion in 2023 and is predicted to reach US$ 6.12 billion by the end of 2033, representing an impressive CAGR of 9.52% from 2024 to 2033. The increasing geriatric population with arthritis is one of the leading causes of chronic lower back pain, which is driving the market’s growth.

Chronic Lower Back Pain Market Revenue 2023 - 2033

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Key Takeaways/ Important Points to Note

  • North America has held a largest revenue share of 48.12% in 2023.

  • By drug class, the non-steroidal anti-inflammatory drugs segment has contributed more than 26% of revenue share in 2023.

  • By drug class, the opioids segment held the second-largest share of the market and is expected to grow at the fastest rate during the forecast period.

  • By route of administration, the oral segment dominated the chronic lower back pain market in 2023.

  • By route of administration, the topical segment is growing significantly in the market.

  • By distribution channel, the retail & online segment dominated the chronic lower back pain market in 2023.

Industry at a Glance

The chronic lower back pain market deals with all the aspects associated with chronic lower back pain, which includes research & development, development of medication, disease monitoring, treatment, and post-treatment care. Even after an original injury or underlying cause of acute low back pain has been addressed, lower back pain that persists for more than 12 weeks or three months is referred to as chronic low back pain (CLBP). In the past ten years, the frequency of CLBP in adults has climbed by over 100%, and as the population ages, it will continue to rise sharply, impacting men and women of all ethnic backgrounds. Some of the main reasons for lower back pain are age, smoking, heredity, degree of fitness, weight increase, and occupational variables, in addition to mental health issues. Healthcare facilities, drug manufacturers, pharmacies, academic institutions, research centers, and assisted living facilities all play a role in the expansion of the chronic lower back pain market.

Top Companies of the Chronic Lower Back Pain Market

  • SpineThera Inc. (U.S.)
  • Pfizer Inc (U.S.)
  • Teva Pharmaceutical Industries Ltd. (Israel)
  • Johnson & Johnson Private Limited (U.S.)
  • Medtronic (Ireland)
  • Endo Pharmaceuticals Inc. (Ireland)
  • Sanofi (France)
  • Merck & Co Inc. (U.S.)
  • Koninklijke Philips N.V. (Netherlands)
  • Vertebral Technologies, Inc. (U.S.)
  • Boston Scientific Corporation (U.S.)
  • Dr. Reddy’s Laboratories Ltd. (India)
  • Astellas Pharma Inc. (Japan)

Recent Achievement by Medtronic

Company Name Medtronic
Headquarters Dublin, Ireland
Recent Development In April 2024, a novel spinal cord implant designed to alleviate chronic pain received approval from the US Food and Drug Administration, according to Medtronic. This move is an attempt to reach a patient group that is mostly dependent on opioid drugs. A novel spinal cord implant designed to alleviate chronic pain was authorized by the US Food and Drug Administration on Friday, marking a significant step forward for Medtronic as it attempts to reach a patient group that is mostly dependent on opioid drugs.

Recent Achievement by Boston Scientific Corporation

Company Name Boston Scientific Corporation
Headquarters Massachusetts, U.S.
Recent Development In February 2024, the FDA authorized an additional indication for the WaveWriterTM SCS Systems to treat persistent low back and leg pain in individuals who have never had back surgery; this condition is known as non-surgical back pain (NSBP), according to a statement released today by Boston Scientific Corporation (NYSE: BSX).

Increasing Obesity, Geriatric Population and Other Factors are the Leading Causes of CLBP

The ailment for which the highest number of people may benefit from rehabilitation is lower back pain (LBP), which is also the biggest cause of disability globally. Any age can suffer LBP, and most individuals will at some point in their lives. The largest age range for LBP patients is between 50 and 55 years old, while the prevalence rises with age up to 80 years old. LBP is more common in females.

Several factors can contribute to back pain, which is driving the growth of the chronic lower back pain market. Those over 30 may experience pain as spinal disks wear down over time. Additionally, excess weight can put pressure on the spine, leading to discomfort. Poor overall health, including weakened muscles and a sedentary lifestyle, can also contribute to back strain. Certain occupations involving heavy lifting or repetitive bending may increase the risk of back injuries. Structural issues like scoliosis can also cause severe back pain. Additionally, a family history of osteoarthritis, certain cancers, and other diseases may raise the risk of low back pain. Mental health can also play a role, as depression and anxiety are known to contribute to back pain. Understanding these risk factors can help individuals take preventive measures to maintain a healthy back.

Global Lower Back Pain Cases from 2020 - 2050 (In Millions)

Limited Treatment Options Limit the Growth of the Chronic Lower Back Pain Market

The limited options for treatment available to individuals with CLBP might have a big impact on patient care. The complexity of lower back pain may be the cause of this limitation. The effectiveness of treatment may vary from person to person. Therefore, it can be difficult to create a strategy that works for everyone. The idea of limited treatment options can also be applied to the accessibility of non-invasive, non-pharmacological interventions, as certain individuals may need or favor complementary therapies like acupuncture, physical therapy, or chiropractic adjustments. Further exploration and innovative ideas in the field of CLBP management are required to tackle this important health concern. If there are no widely accepted therapies that work for everyone, patients and medical professionals may become unsatisfied.

Artificial Discs can be a Great Opportunity for the Growth of the Chronic Lower Back Pain Market

In order to address age-related spinal disc deterioration, which can result in disorders including osteoarthritis, nerve entrapment, and spinal cord compression, advances in spine therapy have led to the development of man-made discs. Conventional therapies, such as spinal fusion surgery, have drawbacks and may cause side effects, including faster disc degeneration in the surrounding area. Simple artificial discs don't have the strength or mobility that they need. Using stem cells in an artificial polymer gel matrix combined with foam is a novel way to mimic the properties of a normal spinal disc. These artificial discs function similarly to normal discs, according to animal experiments where transplanting was successful. Treatment for degenerative spinal disorders and persistent lower back pain may be completely changed by this invention.

Report Highlights

By Drug Class

By drug class, the non-steroidal anti-inflammatory drugs segment dominated the chronic lower back pain market in 2023. Anti-inflammatory, pain, and fever-reducing drugs are known as NSAIDs. Both with and without a prescription, there are several varieties of NSAIDs accessible. They are used by doctors to treat a variety of conditions, such as dental pain, rheumatism, headaches, and strained muscles. Back pain is most commonly treated with NSAIDS, such as naproxen, ibuprofen, and diclofenac. They frequently provide minor relief of symptoms. The over-the-counter market offers these medications in lower dosages. Intranasally given NSAIDs can be taken as a pill form.

By drug class, the opioids segment held the second-largest share of the chronic lower back pain market and is expected to grow at the fastest rate during the forecast period. Opioids are stronger, prescription-only medicines used to treat low back pain if previous therapies are insufficiently effective. Morphine is the opioid most people are familiar with. Buprenorphine, codeine, hydromorphone, oxycodone, tapentadol, tilidine, and tramadol are some other opioids. The potencies of opioids differ. Opioids are incredibly useful in treating a wide range of acute pain conditions.

By Route of Administration

By route of administration, the oral segment dominated the chronic lower back pain market in 2023. Oral medicine administration is a typical way of drug delivery since it has so many advantages. Because it is simple and non-invasive, patients may just take their medication without needing to receive injections or go through other difficult procedures. These are its primary benefits. This might lead to improvements in patient compliance and treatment outcomes overall. Furthermore, taking oral medications on one's own is typically easy, which can ease the burden on doctors and lower healthcare costs. Due to their well-absorbed nature and regular patterns of absorption, oral drugs also make dose calculations and prescription administration simpler. Because of its flexible formulation, which also makes taste masking and extended-release formulations possible, the oral route provides a better overall patient experience.

By route of administration, the topical segment is growing significantly in the chronic lower back pain market. Applying medicine directly to the afflicted region has various benefits when it comes to pain alleviation. First of all, it delivers immediate, focused pain relief where it is most required. It is also simple to use, as it doesn't need to consume tablets or water. Furthermore, topical painkillers often have a better safety profile and milder possible adverse effects when taken as prescribed than oral painkillers. Usually, irritability at the application site is the most frequent adverse effect. If you have any doubts concerning the usage of a topical pain reliever, it's crucial to always read and abide by the product label and speak with a doctor. Topical medications can also be used to treat a variety of pain conditions, such as sprains and strains, back, muscular, neck, and shoulder pain, joint, knee, wrist, and elbow pain, arthritis, and joint pain.

For instance,

  • In April 2024, People may now cure their persistent back pain with BackVive, a new drug-free, easy, over-the-counter (OTC) solution that doesn't require a prescription. A range of small micro-points embedded in a basic adhesive patch serve as pain relief mechanisms. Over 90% of participants in a clinical study showed considerable pain alleviation with BackVive, and several patients saw nearly total elimination of their pain. BackVive uses substances that enter the skin to relieve pain, much like acupuncture. This is accomplished for BackVive using small micro-points that barely penetrate the epidermis, making the procedure almost painless. Like other patches, BackVive is simple to apply and straightforward to use.

By Distribution Channel

By distribution channel, the retail & online segment dominated the chronic lower back pain market in 2023. Personalized consultations are made possible through walk-in interactions with pharmacists. They can provide information about side effects, interactions, and cost-effective substitutes for medications. In order to offer patients a more comprehensive treatment plan, pharmacists frequently collaborate closely with specialists and primary care physicians. Prescriptions may be picked up alongside daily necessities to save time and effort. Through better drug adherence, more affordable prices, enhanced patient accessibility, and more effective prescription administration, online pharmacies can reduce expenses for both patients and the healthcare system. Because they provide safe, legal prescription processing and provide thorough pharmaceutical information, their contributions to the healthcare system ultimately lead to better health outcomes and more efficient use of resources.

Regional Insights

By region, North America dominated the chronic lower back pain market in 2023 with the largest market share. The Centers for Disease Control and Prevention estimate that 50 million individuals in the U.S. suffer from chronic pain, which is defined as persistent pain lasting more than six months. Compared to the general population, persistent pain is more common and severe in veterans. Depression, anxiety, insomnia, a worse quality of life, and drug abuse disorders can all be influenced by chronic pain. It increases the chance of suicide as well. Adults with low back pain have one of the highest rates of disability in the U.S., and their usage of opioids can have negative side effects. A recent bout of back discomfort has been reported by over 65 million Americans. Eight percent of adults, or around 16 million people, have chronic or persistent back pain, which limits their ability to do some daily tasks. The sixth most expensive medical problem in the U.S. is back pain. The annual cost of healthcare and related indirect expenses related to back discomfort exceeds $12 billion. An estimated 83 million workdays are missed annually as a result of back discomfort.

One of the most prevalent chronic illnesses in Canada is back pain. The majority of adults four out of five will at some point in their life have back pain, with the age range of 30 to 50 being the most common cases. Men and women both have back issues on equal occasions. An estimated $6 to $12 billion is spent on medical expenses in Canada alone each year for treating low back pain. This amount does not include the costs incurred by society as a result of worker productivity losses from absences from work and the resulting disability benefits.

Chronic Lower Back Pain Market News

  • In May 2024, AppliedVR, a leader in immersive treatments that are bringing a fresh perspective to medicine, introduced its main prescription medication, RelieVRx®, into workers' compensation. The FDA has cleared the RelieVRx device, the first complete and immersive virtual reality supplementary therapy for persistent lower back pain.
  • In December 2023, the first recommendations for treating low back pain, which affects an estimated 619 million people globally, or one in thirteen, have been announced by the World Health Organization (WHO). The updated recommendations provide medical practitioners a variety of non-surgical therapies that may be used in primary and community care settings, with the goal of improving care quality for the millions of people who suffer from the illness.
  • In August 2023, A clinical-stage biopharmaceutical business called NRx Pharmaceuticals, Inc. submitted an IND application to the FDA in the United States for the use of NRX-101 as a treatment for chronic pain. Utilizing D-cycloserine, a crucial component of NRX-101, as a therapy for chronic pain, the IND application makes use of cutting-edge research in this area.
  • In June 2023, The Horizon PRO range of lower spine braces was introduced by Aspen Medical Products (Aspen), a leader in the field of mobility and pain management solutions, with the goal of reducing symptoms associated with lower back pain brought on by muscular strain and spasms. With Aspen's scientifically proven tri-band technology, the Horizon PRO series offers an improved method of pain treatment. This inelastic design, which is supported by research, increases trunk stability to lessen the strain on overworked muscles, which is important for alleviating excruciating lower back discomfort.

Segments Covered in Chronic Lower Back Pain Market Report

By Drug Class

  • Non-steroidal Anti-inflammatory Drugs
  • Antidepressants
  • Analgesic
  • Opioids
  • Others

By Route of Administration

  • Oral
  • Topical
  • Others

By Distribution Channel

  • Hospital Pharmacies
  • Retail & Online Pharmacies

By Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

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About The Author

Deepa has certified the degree of Master’s in Pharmacy in the Pharmaceutical Quality Assurance department from Dr D.Y. Patil College of Pharmacy. Her research is focused on the healthcare industry. She is the author or co-author of four Review Articles, which include Solid dispersion a strategic method for poorly soluble drugs and solubility improvement techniques for poorly soluble drugs, Herbal Drugs Used In Treatment Of Cataracts, Nano sponges And Their Application in Cancer Prevention and Ayurvedic Remedies of Peptic ulcer. She has also published a Research Article on the Formulation and Evaluation of Mucoadhesive Tablets of Miconazole cocrystal which was published in GIS Science Journal Volume 9 Issue 8. Her passion for secondary research and desire to take on the challenge of solving unresolved issues is making her flourish is the in the research sector.


Physical therapy, home exercise, meditation, proper diet, modification of lifestyle, use of injectables and pharmacologic treatments.

Spine X-ray, MRI, CT scan, electromyography and other tests depending on the cause of the pain.

FDA, World Health Organization, Centers for Disease Control and Prevention, American Association of Neurological Surgeons, National Institute of Health and Bone and Joint Canada.