Towards Healthcare
Ophthalmology Drugs Market Drives USD 45.52 Billion in 2025

Ophthalmology Drugs Market 2025 - 2034 Biologics, AI Integration, and Emerging Opportunities in Eye Care

Based on market forecasts, the global ophthalmology drugs market, projected at USD 43.22 billion in 2024, is expected to reach USD 72.59 billion by 2034, growing at a CAGR of 5.33% over the forecast period. The ophthalmology drugs market is growing due to the rising geriatric population, and North America is dominating because of the rising research & development in drug development.

Category: Therapeutic Area Insight Code: 6037 Format: PDF / PPT / Excel

The global ophthalmology drugs market size is calculated at US$ 43.22 billion in 2024, grew to US$ 45.52 billion in 2025, and is projected to reach around US$ 72.59 billion by 2034. The market is expanding at a CAGR of 5.33% between 2025 and 2034.

Ophthalmology Drugs Market Size 2024 to 2034

It is predicted that the number of persons with eye issues would rise as the senior population grows. The danger of developing a number of eye disorders is greatly increased by the expanding adult population and the rising incidence of diseases like diabetes, which fuels market expansion. The market growth stage is high, and the speed of the market expansion is rising. Because of the quick developments in medication delivery, the ophthalmology drugs market is very innovative. One of the main factors propelling the market is the development of gene treatments as a powerful medication delivery system.

Key Takeaways

  • Ophthalmology drugs sector pushed the market to USD 43.22 billion by 2024.
  • Long-term projections show USD 72.59 billion valuation by 2034.
  • Growth is expected at a steady CAGR of 5.33% in between 2025 to 2034.
  • North America dominated the ophthalmology drugs market in 2024, with a revenue of approximately 42%.
  • Asia Pacific is expected to grow at the fastest CAGR during the forecast period.
  • By drug class, the anti-VEGF biologics segment dominated the market in 2024, with a revenue of approximately 36%.
  • By drug class, the corticosteroids segment is expected to grow at the fastest CAGR during the forecast period.
  • By indication, the retinal disorders segment dominated the market in 2024, with a revenue of approximately 34%.
  • By indication, the dry eye disease segment is expected to grow at the fastest CAGR during the forecast period.
  • By molecule type/modality, the biologics segment dominated the market in 2024, with a revenue of approximately 42%.
  • By molecule type/modality, the small molecule drugs segment is expected to grow at the fastest CAGR during the forecast period.
  • By route of administration, the intravitreal injection segment dominated the ophthalmology drugs market in 2024, with a revenue of approximately 48%.
  • By route of administration, the sustained-release implants/inserts segment is expected to grow at the fastest CAGR during the forecast period.
  • By end-user/channel, the hospitals & specialty ophthalmology clinics segment dominated the market in 2024, with a revenue of approximately 57%.
  • By end-user/channel, the ophthalmic distributors & IDNs segment is expected to grow at the fastest CAGR during the forecast period.

Quick Facts Table

Table Scope
Market Size in 2025 USD 45.52 Billion
Projected Market Size in 2034 USD 72.59 Billion
CAGR (2025 - 2034) 5.33%
Leading Region North America Share 40%
Market Segmentation By Drug Class, By Indication, By Molecule Type / Modality, By Route of Administration, By End User / Channel, By Region
Top Key Players Regeneron Pharmaceuticals, Genentech/Roche, Novartis, Bayer, Bausch + Lomb (Bausch Health), Alcon, AbbVie/Allergan, Santen Pharmaceutical, Apellis Pharmaceuticals, Iveric Bio/Zimura, Oxurion, Kodiak Sciences, Clearside Biomedical, Regenxbio/Gyroscope Therapeutics, Tarsus Pharmaceuticals, Ophthotech / Adverum Biotechnologies, Aerie Pharmaceuticals, Allakos/Harrow Health, Apellis/Iveric/GenSight/MeiraGTx, Generic/Biosimilar & Contract Manufacturers

Market Overview

The ophthalmology drugs market comprises prescription and OTC pharmaceutical products, biologics, and advanced therapies used to prevent, treat, or manage eye diseases and visual disorders. It includes treatments for retinal diseases (AMD, DME, RVO), glaucoma, dry eye, infectious eye diseases, allergic conjunctivitis, ocular inflammation, and inherited retinal disorders. Growth is driven by an aging population, rising prevalence of diabetes and retinal disease, advances in biologics and gene/cell therapies, increasing screening programs, and growing access to ophthalmic care in emerging markets.

Rising Efforts from Key Market Players: The key market players are taking efforts to provide ophthalmology drugs. Various companies are collaborating with each other to develop high-quality drugs. Apart from this, a lot of investments are also being made in drug development.

For instance,

  • In June 2025, SpyGlass Pharma said that a $75 million Series D funding round has been closed. 1. In order to address the need for long-term care of glaucoma and other chronic ocular disorders, SpyGlass says the cash would assist its drug delivery technology, which would enable several years of medical therapy. 
  • In October 2024, Orasis Pharmaceuticals, an up-and-coming ophthalmic pharmaceutical company dedicated to reshaping vision possibilities, announced that $78 million in funding will support the commercial launch of Qlosi™ (pilocarpine hydrochloride ophthalmic solution) 0.4%, a novel corrective eye drop for the treatment of adult presbyopia.

How is AI Transforming the Ophthalmology Drugs Market?

There are revolutionary prospects to address the inherent difficulties and problems of developing tailored therapeutics for eye illnesses by using artificial intelligence (AI) into ophthalmic drug research and development. AI's capacity to handle enormous datasets can make it easier to find new medication candidates, enhance efficacy and safety forecasts, and expedite the drug development process. Applications might include improving predictive toxicity, chemical screening, and target identification.

Market Dynamics

Driver

Rising Eye Diseases are Driving the Ophthalmology Drugs Market

Refractive diseases will affect more than 21.12 million women and 19.14 million men globally by 2040. Refraction diseases are predicted to cause visual loss in 1.8 billion persons worldwide by 2050. More than 700 million people are expected to be blind or suffer from moderate to severe visual impairment (MSVI) by 2050, mostly as a result of the world's population ageing and expanding. An estimated 4.758 billion people will have myopia globally by 2050, with 938 million of those cases being extreme myopia.

Restraint

High Cost of Ophthalmology Drugs

Finding a cost-effective way to assist patients in obtaining the appropriate drugs for their conditions has proven to be a difficulty for physicians. One significant barrier is that eye care providers are unaware of the true out-of-pocket expense of the prescription they are prescribing to their patients. Following an assessment, doctors may be presented with an option between two drugs that are equally effective for a certain ailment, but they have no knowledge of which will be more cost-effective for the patient. Furthermore, even with a discount, certain medications are still very costly for a patient.

Opportunity

Development of New Drug Delivery Systems

The development of new drug delivery systems can increase the growth of the ophthalmology drugs market during the forecast period. In order to make dosing easier and more convenient for patients with glaucoma, dry eye, and other conditions, scientists in the industry are creating a novel, long-lasting, non-invasive medication delivery method. It then highlights some typical studies and suggests improvements in ocular medication delivery mechanisms, particularly those based on nanotechnology. Nanocarriers have many advantages over traditional drug administration, such as the ability to target and deliver genes, overcome ocular barriers, increase transcorneal permeability, prolong drug residence time, decrease drug degradation, decrease dosing frequency, improve patient compliance, and achieve sustained/controlled release.

Segmental Insights

Which Drug Class Segment Dominated the Market in 2024?

By drug class, the anti-VEGF biologics segment was dominant in the ophthalmology drugs market in 2024. The introduction of intravitreally injected biologic drugs (biologics) acting against vascular endothelial growth factor (VEGF) dramatically improved the clinical results of patients with prevalent VEGF-driven retinal disorders. Since 2022, anti-VEGF biosimilars have begun making their way into the U.S. ophthalmology market.

By drug class, the corticosteroids segment is estimated to grow at the highest CAGR during the upcoming period. When it comes to treating ocular inflammation, such as keratitis, conjunctivitis, scleritis, and uveitis, corticosteroids are crucial. Additionally, corticosteroids work well for postoperative inflammation, retinal vein blockage, and diabetic macular edoema. The primary method of delivering ophthalmic corticosteroids, particularly for anterior ocular disorders, is topical administration.

Why the Retinal Disorders Segment Dominated the Market in 2024?

By indication, the retinal disorders segment captured the major share of the ophthalmology drugs market in 2024. Over 410 million individuals worldwide are afflicted with retinal diseases. The most prevalent retinal illnesses are age-related macular degeneration (AMD) and diabetic eye disorders, which together account for more than 40% of all retinal disease cases in the United States. They are the main causes of blindness or vision loss and are become increasingly common as the population ages and the prevalence of diabetes rises.

By indication, the dry eye disease segment is anticipated to achieve the highest growth during the forecast period. Because of the expanding use of visual display terminals (VDTs), such as computers, cellphones, and tablets, DED is becoming a major global public health problem. DED is quite common in many populations across the world; estimates vary from 5% to 50%, depending on the research population and diagnostic standards applied. The frequency is continuously high among young individuals, especially medical students. According to international surveys, the prevalences among medical students in Serbia, Thailand, and India are 60.5%, 70.8%, and 46%, respectively.

What Made the Biologics Segment Dominant in the Market in 2024?

By molecule type/modality, the biologics segment led the ophthalmology drugs market in 2024. Biologics have demonstrated notable effectiveness in the treatment of pan-uveitis and non-infectious posterior uveitis. For NIU, IFX has become one of the most popular biological treatments. For the treatment of ophthalmic disorders, monoclonal antibodies are crucial, but thorough clinical assessment and ongoing innovation are also necessary. To produce safer, more efficient, and more economical therapeutic alternatives, future research should concentrate on creating innovative delivery methods, examining combination treatments, carrying out long-term follow-up studies, and looking into individualised treatment plans.

By molecule type/modality, the small molecule drugs segment is estimated to witness the fastest growth during the forecast period. Solutions, suspensions, emulsions, gels, and ointments are the most often used types of small molecule medication formulations for topical ocular delivery. Small-molecule inhibitors of ocular angiogenesis are required to supplement current treatments.

Why was the Intravitreal Injection Segment Dominant in the Market in 2024?

By route of administration, the intravitreal injection segment held the largest share of the ophthalmology drugs market in 2024. The gold standard for treating a variety of retinal conditions, such as diabetic retinopathy, retinal vein occlusion, and neovascular age-related macular degeneration (AMD), is intravitreal medication administration. Intravitreal injections have been much more common since anti-vascular endothelial growth factor (VEGF) drugs were first developed. It is crucial to become proficient in the method required to carry out this surgery correctly in order to maximise patient safety and lower the possibility of problems.

By route of administration, the sustained-release implants/inserts segment is estimated to be the fastest-growing during the forecast period. From the standpoint of formulation, sustained-release technologies would be very beneficial to patients and physicians since they would improve IOP control for more than twenty-four hours, eliminate poor adherence, and minimise adverse effects. Drug delivery through intraocular implants might continue for months or even years. They may frequently be injected using a less invasive technique and are ideal for a clinical context.

Which End-User Segment Dominated the Market in 2024?

By end-user/channel, the hospitals & specialty ophthalmology clinics segment dominated the ophthalmology drugs market in 2024. They are committed to giving people of all ages top-notch eye treatment. To guarantee that patients receive the most cutting-edge care possible, it is made up of a group of highly qualified and experienced ophthalmologists, optometrists, and technicians who have received training in the newest diagnostic and therapeutic methods. Additionally, the department at hospitals and clinics is dedicated to remaining at the forefront of ophthalmology-related technical breakthroughs.

By end-user/channel, the ophthalmic distributors & IDNs segment is anticipated to achieve the highest CAGR during 2025-2024. In the supply chain for eye care goods, ophthalmic distributors are essential because they link producers with healthcare providers, such as Integrated Delivery Networks (IDNs). Groups of hospitals and other healthcare institutions known as IDNs sometimes depend on distributors to get a variety of ophthalmic supplies and equipment.

Regional Insights

Ophthalmology Drugs Market Share, By Region, 2024 (%)

What Made North America Dominant in 2024?

North America dominated the ophthalmology drugs market share 42% in 2024. A increased frequency of eye illnesses and growing awareness of these conditions are two of the elements contributing to this region's rise. Significant R&D efforts by major market participants have been conducted in the area, which has aided in its expansion. Further supporting the North American market are the presence of prominent firms like Bausch & Lomb, Pfizer Inc., and Alcon.

U.S. Ophthalmology Drugs Market Trends

An additional 50.2 million Americans are undiagnosed and have not gotten treatment from qualified eye specialists, while 16 million Americans suffer from dry eye syndrome, which costs the healthcare system USD 52 billion yearly. As people age, the illness becomes more prevalent; 8.4% of those under 60, 15% of those between 70 and 79, and 20% of those over 80 are affected. According to CDC estimates, medical, nursing care, and supporting services account for $98.7 billion of the $134.2 billion annual economic burden of vision loss and blindness in the United States.

Canada Ophthalmology Drugs Market Trends

In November 2024, members of the public are more familiar with Bill C-284, the National Strategy for Eye Care Act, which was enacted by the Canadian Parliament. The Canadian Ophthalmological Society's news statement praised the action by activists for eyesight health. Furthermore, eight million Canadians today suffer from one of the top four eye conditions: glaucoma, cataracts, diabetic retinopathy, or age-related macular degeneration, according to the Canadian Ophthalmological Society. The National Strategy for Eye Care Act is a vital step in preserving the well-being and standard of living of diabetics.

Rising Geriatric Population is Driving the Asia Pacific

Asia Pacific is estimated to host the fastest-growing ophthalmology drugs market during the forecast period. driven by expanding access to eye care services, growing healthcare spending, and sizable patient populations. China, Japan, India, Australia, and South Korea are just a few of the many markets in the area; each has its own healthcare dynamics and market traits. The market is growing as a result of increased acceptance of cutting-edge ophthalmic therapies, better healthcare infrastructure, and growing awareness of eye health. Growing research and development efforts as well as the rise in both local and foreign pharmaceutical enterprises are also advantageous to the region.

Ophthalmology Drugs Market Value Chain Analysis

R&D

Finding and creating possible therapeutic candidates, manufacturing the medication, performing clinical trials, and identifying disease targets are some of the crucial steps in ophthalmology drug research and development. Along with making sure the medication satisfies certain ophthalmic needs like sterility and eye comfort, this procedure also involves optimising drug delivery techniques.

Top Companies: Allergan (now part of AbbVie), Novartis, Bausch + Lomb, and Alcon (a division of Novartis).

Clinical Trials and Regulatory Approvals

Preclinical research, clinical trials (Phases 1-3), and a New Drug Application (NDA) evaluation by regulatory agencies such as the FDA are all steps in the multi-stage process that goes into developing and approving medications for ophthalmology. For continuous safety monitoring, post-market surveillance (Phase 4) is also essential.

Top Companies: Ora, Inc., Lindus Health, ICON plc, PPD (Thermo Fisher Scientific), Syneos Health, and Labcorp Drug Development.

Packaging and Serialization

In order to maintain patient safety and regulatory compliance, ophthalmology medication packaging and serialisation require careful consideration of sterility, material selection, and serialisation parameters.

Top Companies: Alcon, Johnson & Johnson, Novartis, Bausch & Lomb, and Allergan (now part of AbbVie). 

Patient Support and Services

Education, help with administration, and addressing any adherence challenges are all part of patient care and services in ophthalmology, especially when it comes to medication administration. This include educating patients about medication combinations, making sure they know how to administer their eye drops properly, and giving assistance to people who have cognitive or physical impairments.

Top Companies: Allergan (now AbbVie), Bausch + Lomb, Novartis, Alcon, Johnson & Johnson Vision, Santen Pharmaceutical, and Cipla.

Top Companies in the Ophthalmology Drugs Market

Ophthalmology Drugs Market Companies

  • Regeneron Pharmaceuticals
  • Genentech/Roche
  • Novartis
  • Bayer
  • Bausch + Lomb (Bausch Health)
  • Alcon
  • AbbVie/Allergan
  • Santen Pharmaceutical
  • Apellis Pharmaceuticals
  • Iveric Bio/Zimura 
  • Oxurion
  • Kodiak Sciences
  • Clearside Biomedical
  • Regenxbio/Gyroscope Therapeutics
  • Tarsus Pharmaceuticals
  • Ophthotech / Adverum Biotechnologies
  • Aerie Pharmaceuticals
  • Allakos/Harrow Health
  • Apellis/Iveric/GenSight/MeiraGTx
  • Generic/Biosimilar & Contract Manufacturers

Latest Announcements by Industry Leaders

In June 2025, new treatments and research will be supported by an unprecedented $40 million donation to the CU Anschutz Department of Ophthalmology. "As the chair of the CU Department of Ophthalmology and the Sue Anschutz-Rodgers Endow Chair in Retinal Diseases, we have a fantastic opportunity to drive our research enterprise, which is essential to clinical care," stated Naresh Mandava, MD. With your contribution, we will be able to get technologies from the lab to the patient more quickly than previously.

Recent Developments in the Ophthalmology Drugs Market

  • In June 2025, series C investment of AUD $40 million has been obtained by PolyActiva to support the ongoing clinical development of PA5108, its primary ocular implant candidate. The PA5108 is a sustained-release, biodegradable ocular implant that lowers intraocular pressure (IOP) in patients with glaucoma and ocular hypertension by delivering latanoprost.
  • In July 2024, a leading ophthalmic gene therapy firm dedicated to saving and restoring the eyesight of patients suffering from blinding retinal illnesses, Beacon Therapeutics Holdings Limited (‘Beacon Therapeutics’ or ‘the firm’) announced today that it has secured $170 million in Series B investment.

Segments Covered in the Report

By Drug Class

  • Anti-VEGF Biologics (e.g., ranibizumab, aflibercept, brolucizumab, newer long-acting agents)
  • Corticosteroids (intravitreal & topical)
  • Prostaglandin Analogs (glaucoma)
  • Beta-Blockers, Carbonic Anhydrase Inhibitors, Alpha Agonists (glaucoma)
  • Cyclosporine / Lifitegrast & other immunomodulators (dry eye)
  • Antibiotics / Antivirals (topical/systemic)
  • Rho kinase (ROCK) inhibitors & other novel IOP-lowering classes
  • Gene & Cell Therapy Products

By Indication

  • Retinal Disorders (AMD, DME, RVO)
  • Glaucoma
  • Dry Eye Disease
  • Ocular Infection (bacterial, viral)
  • Allergic Conjunctivitis
  • Uveitis & Ocular Inflammation
  • Inherited Retinal Diseases

By Molecule Type / Modality

  • Biologics (monoclonal antibodies, fusion proteins)
  • Small Molecule Drugs
  • Long-Acting Implants & Depot Formulations
  • Gene Therapies (AAV, lentiviral)
  • Cell Therapies & Regenerative Approaches

By Route of Administration

  • Intravitreal Injection
  • Topical (eye drops)
  • Sustained-release Implants/Inserts
  • Periocular/Subconjunctival Injection
  • Systemic

By End User / Channel

  • Hospitals & Specialty Ophthalmology Clinics
  • Ambulatory Surgical Centers (ASC)
  • Retail Pharmacies & Specialty Pharmacies
  • Ophthalmic Distributors & IDNs 
  • Online Pharmacies & DTC channels

By Region 

  • North America
    • U.S.
    • Canada
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Thailand
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Sweden
    • Denmark
    • Norway
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East and Africa (MEA)
    • South Africa
    • UAE
    • Saudi Arabia
    • Kuwait
  • Last Updated: 22 August 2025
  • Report Covered: [Revenue + Volume]
  • Historical Year: 2021-2023
  • Base Year: 2024
  • Estimated Years: 2025-2034

Meet the Team

Rohan Patil is a seasoned market research professional with over 5+ years of focused experience in the healthcare sector, bringing deep domain expertise, strategic foresight, and analytical precision to every project he undertakes.

Learn more about Rohan Patil

Aditi Shivarkar is a seasoned professional with over 14 years of experience in healthcare market research. As a content reviewer, Aditi plays a critical role in ensuring the quality and accuracy of all market insights and data presented by the research team.

Learn more about Aditi Shivarkar

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FAQ's

The ophthalmology drugs market holds a valuation of USD 45.52 billion as of 2025, and will expand to USD 72.59 billion by 2034, achieving a CAGR of 5.33% between 2024 and 2034.

North America is currently leading the ophthalmology drugs market due to rising clinical trials in ophthalmology.

The ophthalmology drugs market includes six segments such as by drug class, by indication, by molecule modality, by route of administration, by end-user channel, and by region.

Some key players include Regeneron Pharmaceuticals, Genentech Roche, Novartis, Bayer, Oxurion, etc.

Key trends include a growing geriatric population and, rise in eye diseases due to occupational hazards.

Ministry of Health and Family Welfare, Government of India, National Institutes of Health, FDA, WHO, PIB, CDC.