| Company | Headquarter | Estimated Annual Revenue | Year |
| Talkspace | New York City, New York, U.S. | $187.6 million |
2024 |
| BetterHelp (Teladoc) | Dallas, Texas, U.S. | $1.13 million | 2023 |
| Lyra Health | Burlingame, California, U.S. | $235 million | 2024 (Estimated) |
Headquarters: New York City, NY, USA.
Established: 2012 (founders Roni & Oren Frank).
Focus: text/video-based therapy and enterprise/payer partnerships for digital behavioral health.
Unlimited messaging therapy subscription, scheduled video sessions, employer & health-plan integrations, clinician network and care pathways.
Early mover in message-based therapy; broad B2B/payer distribution; publicly listed with transparent financial reporting.
Scale enterprise and payer contracts; integrate stepped-care pathways; expand specialty referrals and value-based partnerships.
Quality/regulatory scrutiny on outcomes and privacy; competition from larger telehealth players; clinician supply constraints.
Reported full-year 2024 revenue growth and launched strategic partnerships and consortiums to strengthen specialty referral networks.
Headquarters: Mountain View, CA, USA (BetterHelp); acquired by Teladoc Health (parent) in 2015.
Established: 2013 (founders Alon Matas & Danny Bragonier).
Focus: consumer-focused online therapy and counseling at scale.
Web- and app-based therapy (messaging, phone, video), employer/benefit offerings via Teladoc integration.
Large user base and brand recognition; deep distribution via Teladoc channels and employer/podcast marketing reach.
Deeper integration with Teladoc’s clinical/telehealth stack; insurer and employer contracts; productizing outcomes for payers.
Privacy and data-use scrutiny, higher customer-acquisition costs, regulatory and reputational headwinds tied to parent performance.
Continued integration into Teladoc’s portfolio and shifting business focus toward payer/employer agreements amid parent-company strategic adjustments.
Headquarters: United States (national footprint).
Established: 2020.
Focus: integrated tele-mental health (therapy + medication management + coaching).
Remote therapy, psychiatry/medication management, coaching, care teams and measurement-based care.
Rapid scaling and integrated care model combining therapy and medication; focus on measurable outcomes.
Leverage outcome data to win payer contracts; expand chronic mental-health programs and specialty care.
Regulatory oversight for prescribing at scale; trust-restoration after industry scrutiny of teleprescribing models.
Continued product investments to integrate measurement-based care and broaden clinician network.
Headquarters: Santa Monica, CA & global offices.
Established: Headspace founded 2010; merged with Ginger (2021) to form Headspace Health.
Focus: mindfulness, meditation, digital mental health services and enterprise behavioral health.
Headspace meditation app; Headspace Care (formerly Ginger) — coaching, therapy, psychiatry; clinical programs (e.g., CBT-I sleep programs).
Strong consumer brand and content library; combined clinical capabilities after Ginger acquisition; broad D2C + B2B channels.
Convert large engaged D2C user base to employer/payer offerings; commercialize clinical programs (eg, sleep, anxiety) for health plans.
Balancing consumer product and clinical services; pressure on growth/margins in competitive market.
Ongoing product and clinical program expansion (including sleep/CBT-I programs) and ongoing enterprise pushes following the Ginger integration.
Headquarters: Burlingame / Bay Area, CA, USA.
Established: 2015.
Focus: employer mental health benefits and evidence-based clinical care.
Coaching, therapy, psychiatry, digital CBT tools, care navigation and measurement of outcomes for employers.
Strong employer partnerships; emphasis on evidence-based care and measurable outcomes.
International expansion and adding chronic-condition mental health programs; outcome-based contracting with large employers.
Cost of provider network scaling; demonstrating long-term ROI to cost-sensitive buyers.
Continued expansion of clinical pathways and product bundles targeting large employers.
Headquarters: originally San Francisco, CA; now integrated into Headspace Care.
Established: 2011.
Focus: on-demand coaching, therapy and clinical pathways via mobile-first model.
24/7 coaching, therapy, psychiatry, analytics and employer-facing care navigation.
On-demand coaching model; strong outcomes data for stepped care; enterprise adoption.
Bundled offerings with Headspace for full-spectrum mental health and wellbeing for employers.
Harmonizing product offerings within Headspace and reducing duplicate services.
Full integration into Headspace Care and continued refinement of stepped-care offerings.
Headquarters: New York, NY, USA.
Established: 2016.
Focus: employer mental-health benefit using AI-driven matching and outcomes measurement.
Personalized care matching, therapy, coaching, psychiatry, and technology for employers and health plans.
AI-driven matching that improves treatment fit; strong employer traction and valuation growth.
Productizing AI outcomes to lock in long-term employer contracts and widen population reach.
Market competition for employer dollars; need to continuously prove outcome improvements and ROI.
Ongoing AI and data investments and high-profile funding/valuation milestones as it scales.
Headquarters: San Francisco, CA, USA.
Established: 2017 (founder Dr. Alison Darcy).
Focus: AI-driven conversational agent (chatbot) for scaled mental health support.
Woebot app (CBT-informed conversational agent), clinical studies for outcomes, enterprise/licensed deployments.
Scalable 24/7 conversational interface; extensive user base and published research showing short-term symptom reductions.
Embed with employer benefits and digital therapeutics pathways; expand language/market coverage.
Demonstrating durable clinical impact compared to human care; regulatory questions around AI-driven care.
New product rollouts and continued clinical validation and enterprise partnerships.
Headquarters: U.K. / U.S. presence; founded by Professor Colin Espie and Peter Hames (origins ~2010).
Established: c.2010 (product-first growth).
Focus: evidence-based digital therapeutics for insomnia and anxiety.
Sleepio (digital CBT for insomnia), Daylight (digital CBT for anxiety), Spark Direct and other DTx offerings.
Strong clinical evidence base and NHS/health-plan adoption in several markets.
Scale DTx reimbursements, expand to adolescent care (via sibling acquisitions).
Securing sustainable reimbursement models and continued clinical adoption.
Selected for multiple digital health formularies and ongoing NHS & payer integrations; acquired Limbix (adolescent DTx) to expand product portfolio.
Headquarters: originally Dublin/UK research roots; now part of Amwell (Boston, MA).
Established: platform roots ~2006–2012 (academic origins) and acquired by Amwell in 2021.
Internet-delivered CBT platform for anxiety, depression and long-term behavioral health programs used by health systems and payers.
Two decades of academic/clinical research validating digital CBT; enterprise-grade deployments via Amwell.
Integrate into Amwell’s telehealth ecosystem and scale across US health systems.
Competition from US-based DTx and commercial mental-health platforms.
Integration into Amwell’s platform following 2021 acquisition and scaling within digital health formularies.
Headquarters: New York, NY, USA.
Established: 2014.
Focus: value-based behavioral-health enablement and care coordination between medical and behavioral providers.
Risk identification, provider network, care navigation, analytics and whole-person care coordination for payers and health systems.
Strong payer and health-system relationships; focus on clinical integration and referral pathways.
Expand value-based contracts, deepen clinical integration with EHRs and scale to more states.
Integrating disparate provider networks and showing clear financial return on integrated care.
Continued enterprise deployments and platform enhancements; later organizational developments and acquisition activity in the behavioral-health enablement space.
Headquarters: San Francisco, CA, USA.
Established: 2017.
Focus: personalized psychiatry and therapy primarily for anxiety and depression.
Virtual psychiatry, therapy, medication management, and personalized digital therapeutic programs.
Clinical focus on mood disorders and integrated therapy + med management.
Broaden employer/payer distribution and demonstrate outcomes for more severe mood conditions.
Competition from both virtual psychiatry incumbents and integrated platforms; reimbursement complexity.
Productization of personalized psychiatry and expansion of clinically-proven therapy programs.
Headquarters: offices in San Mateo (CA), Denver (CO), and Helsinki (Finland); founded by Scandinavian and US team.
Established: ~2015–2016.
Focus: 12-week holistic digital mental health program that combines therapists, biofeedback and coaching.
12-week guided program for depression/anxiety/stress, clinician support via app, biofeedback wearables and peer communities.
Holistic, clinically evaluated program and wearable-enabled interventions.
Expand employer and payer channels; publish more outcome studies to secure reimbursement.
Scaling clinician availability and demonstrating cost-effectiveness vs traditional therapy.
Published 2024 outcomes showing promising symptom reductions for completers and continued program iterations.
Headquarters: New York City, NY, USA.
Established: company roots started ~2012 (consumer Happify) and corporate/clinical spinouts followed; Happify Health (enterprise/clinical) operates in mental health and digital therapeutics.
Evidence-based digital programs for resilience, behavior change and mental health used by consumers and enterprise customers.
Behavioral-science foundation and a consumer-tested content library; enterprise distribution.
Move into reimbursement pathways and clinical partnerships for chronic behavioral health.
Translating consumer engagement into durable clinical outcomes and sustained revenue.
Continued enterprise expansion and platform evolution; varying revenue estimates in the public domain.
Headquarters: Menlo Park / Bay Area, CA (historically).
Established: ~2013–2014.
Focus: originally clinical biomarkers using passive smartphone data + tele-mental health.
Digital platform combining behavioral-data signals and clinical care (historically); business model shifted over time.
Early pioneer in behavioral digital biomarkers and high-profile funding rounds.
If restructured, the tech could support measurement-based care and passive monitoring for risk detection.
Organizational and funding difficulties, layoffs and operational contractions in recent years; uncertain status as of recent reporting.
Experienced major restructuring and workforce reductions; industry commentary centers on lessons learned for digital biomarker startups.
Headquarters: U.S. operational HQ historically in California; founded 2013.
Established: 2013 (founder: Glen Moriarty).
Focus: large volunteer listener network + on-demand chat support and licensed therapy.
Peer-listener chat services, moderated community, and paid therapy/online counseling for users.
Massive global volunteer listener community; low-cost, scalable emotional support.
Funnel peer-support users into paid clinical care and enterprise support programs.
Quality control for non-clinical listeners and competition from paid teletherapy platforms.
Expanded language coverage and enterprise licensing; continued growth of trained listener base.
Headquarters: Cambridge, MA / Tel Aviv (global presence).
Established: around 2019–2020.
Focus: AI-powered documentation and workflow automation specifically for behavioral health providers.
AI documentation assistant (progress notes automation), compliance tools, clinical insights and workflow integrations for providers and health systems.
Domain-specific AI trained on behavioral-health data; reduces clinician administrative burden and boosts compliance.
Large market in provider-side automation; potential to become standard clinical-documentation tool for behavioral health.
Integration with legacy EHRs, regulatory/compliance scrutiny and proving ROI across community behavioral health orgs.
Raised a significant Series C in 2025 and launched enhanced compliance product lines for clinical documentation review.
Headquarters: San Francisco, CA (global reach).
Established: 2017.
Focus: employer mental health benefits spanning coaching, therapy, assessments and self-serve tools.
One-on-one coaching/therapy, group sessions, self-guided programs, crisis support and analytics for employers.
Holistic, multi-modal offering for employers; global delivery and UX-focused platform.
Broaden into clinical outcomes products and value-based pricing with large employer groups.
Competitive market for employer mental-health budgets and proving persistent ROI.
Continued expansion of service channels, international deployments and employer partnerships.
Headquarters: San Francisco / Palo Alto area, CA.
Established: 2016.
Focus: prescription digital therapeutics (PDTs) for adolescent mental health.
SparkRx / Spark (digital therapeutic for adolescent depression), clinician tools and evidence-based digital interventions.
First-to-market pediatric/adolescent DTx focus; strong clinical trial evidence for SparkRx.
Pathways to prescription/reimbursement for adolescent mental-health DTx and integration with school/paediatric systems.
Regulatory and reimbursement hurdles for pediatric DTx and scaling clinician adoption.
Acquired by Big Health in 2023 to accelerate adolescent DTx scale and distribution.
The global digital behavioral health market size is calculated at USD 27.9 billion in 2024, grew to USD 33.1 billion in 2025, and is projected to reach around USD 153.85 billion by 2034. The market is expanding at a CAGR of 18.6% between 2025 and 2034.
Government Investment: Government bodies provide funding to private institutions to promote digital mental health services and increase their accessibility.
Increasing Collaborations: Public-private partnerships among government organizations/regulatory bodies and private organizations provide desired support and accelerate the use of digital health tools in respective nations.
Michael Jablonski, Vice President of Clinical Development & Medical Affairs at Boehringer Ingelheim, commented on collaborating with the Center for Technology and Behavioral Health (CTBH) that the collaboration aims to elevate the promise of prescription digital therapeutics to positively impact the health and quality of life of individuals living with serious mental illness and provide easier access to care. He also stated that the company aims to deliver more integrated and tailored solutions, enabling better outcomes.
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