Towards Healthcare
Lentiviral Vector Market Size Skyrockets 18.56% CAGR by 2034

Lentiviral Vector Market Outlook Strategic, Trends, Growth Forecast and AI Adoption

Market insights predict, the lentiviral vector industry is expected to grow from USD 360 million in 2024 to USD 1943.24 million by 2034, driven by a CAGR of 18.56%. The lentiviral vector market is expanding due to growing awareness as well as rising demand for T-cell therapies. North America led the market due to the presence of the advanced healthcare sector.

Category: Biotechnology Insight Code: 5637 Format: PDF / PPT / Excel

Lentiviral Vector Market Size, Growth, Opportunities and Segment Analysis

The global lentiviral vector market size is calculated at USD 360 million in 2024, grew to USD 426.82 million in 2025, and is projected to reach around USD 1943.24 million by 2034. The market is expanding at a CAGR of 18.56% between 2025 and 2034.

Lentiviral Vector Market Size 2024 - 2034

Key Takeaways

  • By 2024, the lentiviral vector market will likely exceed USD 360 million.
  • Valuation is projected to hit USD 1943.24 million by 2034.
  • Estimated to grow at a CAGR of 18.56% starting between 2025 to 2034.
  • North America dominated the global lentiviral vector market share by 46% in 2024.
  • Asia Pacific is expected to be the fastest-growing during the forecast period.
  • By product type, the 1st-generation segment dominated the market share in 2024.
  • By product type, the 3rd-generation segment is estimated to grow significantly at a notable CAGR during the forecast period.
  • By indication type, the HIV segment dominated the market in 2024.
  • By indication type, the Β-thalassemia segment is anticipated to grow significantly during the forecast period.
  • By end user, the research institutes segment dominated the global lentiviral vector market in 2024.
  • By end user, the hospital segment is predicted to be the fastest growing during the forecast period.

Key Metrics and Overview

Metric  Details
Market Size in 2025 USD 426.82 Million
Projected Market Size in 2034 USD 1943.24 Million
CAGR (2025 - 2034) 18.56%
Leading Region North America Share by 46%
Market Segmentation By Product Type, By Indication, By End User, By Region
Top Key Players Thermo Fisher Scientific Inc., Cobra Biologics Limited, Merck KGaA, Sirion-Biotech GmbH, OriGene Technologies Inc., FinVector Oy, Sino Biological Inc., Oxford Biomedica, Lonza, Cell Biolabs, GENEMEDI, Batavia Biosciences B.V., Cytiva, Takara Bio Inc., Sirion-Biotech GmbH (Revvity), Waisman Biomanufacturing, Vector Biolabs

Market Overview

The research conducted on lentiviral vectors is increasing. At the same time, new gene therapies developed by using lentiviral vectors are moving towards clinical trials after successful preclinical trials. Furthermore, trials on beta thalassemia, AIDS, and Wiskott–Aldrich are also being conducted. Similarly, various animal models are also being treated with lentiviral vector-based gene therapy, suffering from cognate human diseases. The SIN lentiviral vectors also provided improved safety profiles over γ-RVs. Thus, with the help of lentiviral vectors, new, improved therapeutics are being used in the treatment of various incurable diseases.

Which New Partnerships Were Announced in the Lentiviral Vector Market?

  • In May 2025, a partnership between AGC Biologics and Quell Therapeutics ("Quell") was announced. For the treatment of severe immune disorders, the development of numerous Treg cell therapy drug candidates will be supported by this partnership. Furthermore, for CTA / IND submissions, the lentiviral vector (LVV) material by the proprietary ProntoLVVtm platform of AGC Biologics will be provided for the development of these therapies. (Source - Le Lezard)
  • In May 2025, a partnership between Genezen and Optieum Biotechnologies, Inc. (Optieum) was announced, where they will work together in cGMP manufacturing of the lentiviral vector (LVV) construct, which is used to produce a novel CAR-T therapy for glioblastoma treatment that is OPTF01. (Source - CISION)

What Is the Role of AI In the Lentiviral Vector Market?

AI plays an important role in the lentiviral vector market in the identification of genetic data, target sites, as well as it also enhances the safety and efficiency of the products developed using lentiviral vectors. The AI algorithm, as well as machine learning (ML), are used in detecting the gene sequence, or target sites, for enhancing the treatment. Moreover, it can also predict the risk involved with the treatment options, which in turn enhances the safety and efficiency of the products. Furthermore, it is also used in the production process, which reduces errors and increases the yield obtained.

Market Dynamics

Driver

Rising Awareness

Along with the increasing incidences of diseases, the awareness about early diagnosis as well as effective treatment approaches is increasing the demand for lentiviral vectors. At the same time, various awareness programs and campaigns are being conducted by governments and the private sector. This, in turn, increases the need for the use of personalized medications or gene therapies, which are developed with the help of lentiviral vectors. Furthermore, they are also being used in the production of various vaccines. Thus, this promotes the lentiviral vector market growth.

Estimated Percentage of People Aware of Their HIV

The graph represents a comparison between the estimated percentage of people aware of their HIV in year of 2023 and 2025. It indicates that there will be a rise in HIV awareness. Hence, it increases the demand for the use of lentiviral vector-based treatment options for the effective management of HIV. Thus, this in turn will ultimately promote the market growth.

Restraint

High Cost

The lentiviral production process involves multiple steps as well as sophisticated equipment, which may be expensive. Moreover, the yield obtained is very low due to which makes it more costly. Hence, when these vectors are further used in the development of various therapies, the cost adds up. At the same time, the process involved in the clinical trials is also expensive. Thus, all these factors result in making the vectors expensive.

Opportunity

Increasing T-Cell Therapies

Due to the increasing genetic diseases, the demand for cell and gene therapies has increased. This, in turn, increased the use of lentiviral vectors for the development of these therapies. Thus, to enhance the targeted drug delivery by CAR-T cell therapies, lentiviral vectors are being used. Furthermore, it also increases the duration of action. Similarly, due to these advantages, it is also being used in the development of various other treatment approaches. Thus, all these factors increase the use of lentiviral vectors, which in turn also increase the research conducted. Hence, this promotes the lentiviral vector market growth.

For instance,

  • In April 2025, by utilizing an enhanced digital PCR (dPCR) workflow, QIAGEN is expanding its cell and gene therapy (CGT) portfolio, which includes solutions for lentivirus-based applications like personalized cancer immunotherapy, that is chimeric antigen receptor T-cell (CAR-T). (Source - 01net.)

Segmental Insights

1st-Generation Segment Led in 2024

By product type, the 1st-generation segment dominated the market in 2024. The 1st-generation products were widely used in 2024, due to their enhanced stability, efficiency, as well as safety. This, in turn, contributed to the market growth.

3rd-Generation Segment: Significantly Growing

By product type, the 3rd-generation segment is estimated to grow significantly at a notable CAGR during the forecast period. The 3rd-generation products are being used in the development of various cell and gene therapies due to their improved safety and stability.

HIV Segment Dominated in 2024

By indication type, the HIV segment dominated the market in 2024. Due to increasing incidences of HIV, various research and development studies were conducted using lentiviral vectors. This enhanced the market growth.

Β-Thalassemia Segment: Significantly Growing

By indication type, the Β-thalassemia segment is anticipated to grow significantly during the forecast period. Various new therapies are being developed with the help of lentiviral vectors for treating Β-thalassemia as they may target the defective gene.

Research Institutes Segment Dominated

By end user, the research institutes segment dominated the global lentiviral vector market in 2024. The research institutes were driven by the increased interest in the development of new lentiviral vector-based therapies. This promoted the market growth.

Hospital Segment: Fastest Growing

By end user, the hospital segment is predicted to be the fastest growing during the forecast period. The hospitals are providing lentiviral vector-based cell, gene therapies as well as personalized medications, accelerating the market growth.

Regional Insights

Lentiviral Vector Market Share, By Region, 2024 (%)

Advanced Healthcare Sector Drives North America

North America dominated the lentiviral vector market share by 46% in 2024. North America consisted of well-developed healthcare sectors with advanced technologies as well as skilled personnel. This, in turn, increased various treatment approaches by using lentiviral vectors. Thus, this contributed to the market growth.

The U.S. Lentiviral Vector Market Trends

The industries in the U.S are developing various new therapies with the help of lentiviral vectors for effective treatments of rising genetic diseases. At the same time, the government is also providing its support for making these treatment options easily accessible.

The Canada Lentiviral Vector Market Trends

As the healthcare sector in Canada is advanced, it is using various technologies for conducting research for the development of new applications of lentiviral vectors. Furthermore, growing cancer cases are also increasing their demand, which leads to rising collaborations.

Increasing Diseases Boost the Asia Pacific

Asia Pacific is estimated to host the fastest-growing lentiviral vector market during the forecast period. Asia Pacific is experiencing a rise in disease occurrences in the population. Due to this, there is a rise in the demand for the use of personalized as well as other treatment options using lentiviral vectors. Thus, this is enhancing the market growth.

The China Lentiviral Vector Market Trends

As China has a large population, the incidence of diseases also increases. Therefore, by using advanced technologies, the industries are developing new treatment approaches, as well as hospitals are also adopting various cell and gene therapies developed by lentiviral vectors.

The India Lentiviral Vector Market Trends

The growing diseases in India are driving the demand for new personalized and gene or cell therapies. This increases the use of lentiviral vectors in their development. This is further supported by the government to make the treatment affordable.

Europe Driven by Growing Research

Europe is expected to grow significantly in the lentiviral vector market during the forecast period. The industries as well as institutions in Europe are focusing on the development as well as detection of other applications of lentiviral vector use. Furthermore, the rule and regulations also enhance these workflows. Thus, this promotes the market growth.

For instance,

  • In July 2024, as per TASS, a new medicine for the treatment of Human Immunodeficiency Virus (HIV) is being developed by the experts of Russia’s Federal Medical and Biological Agency (FMBA), which is based on a lentiviral vector. This medicine will show minimal side effects, prolonged therapeutic effect, and no drug resistance. (Source - Russian News Agency)

The Germany Lentiviral Vector Market Trends

The industries in Germany are developing new therapies using advanced technologies, which is increasing the interest in institutes as well. At the same time, due to stringent regulations, the safety and efficiency of these therapies are also enhanced.

The UK Lentiviral Vector Market Trends

The institutes as well as the industries present in Germany are researching new applications of lentiviral vectors along with increased development of cell, gene therapies, and personalized medication. Moreover, these are supported by the government investments.

Top Companies in the Lentiviral Vector Market

Lentiviral Vector Market Companies

What are the Latest Announcements or Statements by Major Players?

  • In May 2025, the CEO of Vector BioMed, Dr. Dropulic, stated that, to pull science forward (to market), along with innovators, the use of innovative and cost-effective vector production in gene therapy is needed. Thus, to support CGT developers during every stage, they are presenting a true, right-the-first-time sentiment, as well as developing a more integrated ecosystem with the help of LENTIVERSE. (Source - Le Lezard)
  • In May 2025, the Co-founder of VintaBio, M.S., M.B.A., Junwei Sun, stated that vector manufacturing must be transformed for unlocking the complete potential of gene therapy. Thus, with the use of extended vector production duration in their perfusion-based adherent approach helps in enhancing full capsid content. This, shift enhances the scalability, manufacturing, and decreases the complexities during the process. (Source - BioSpace)

Recent Developments in the Lentiviral Vector Market

  • In April 2025, the opening of the University College London (“UCL”) clinical trial was announced by ViroCell Biologics for the new chimeric antigen receptor (CAR) T-cell therapy developed by Professor Persis Amrolia against relapsed paediatric acute lymphoblastic leukaemia (ALL). (Source - BioSpace)
  • In May 2025, a new lentiviral vector pseudotyped with the MxV glycoprotein (MxV-G) was developed by Immunofoco's team, which is used to develop CAR-T cells in vivo. This innovation enhances the viral titer, transduction efficiency, as well as makes the CAR-T cells to more effective in targeting and killing the tumor cells, compared to traditional VSV-G. (Source - Taiwan News)

Segments Covered in the Report

By Product Type

  • 1st-Generation
  • 2nd-Generation
  • 3rd-Generation

By Indication

  • HIV
  • Β-Thalassemia
  • X-Linked Adrenoleukodystrophy
  • Metachromatic Leukodystrophy
  • Wiskott-Aldrich Syndrome

By End User

  • Hospitals
  • Clinics
  • Research Institutes

By Region

  • North America 
    • U.S.
    • Canada
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Thailand
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Sweden
    • Denmark
    • Norway
  • Latin America
    • Brazil Mexico
    • Argentina
  • Middle East and Africa (MEA)
    • South Africa
    • UAE
    • Saudi Arabia
    • Kuwait
  • Last Updated: 23 May 2025
  • Report Covered: [Revenue + Volume]
  • Historical Year: 2021-2023
  • Base Year: 2024
  • Estimated Years: 2025-2034

Meet the Team

Shivani Zoting is a dedicated research analyst specializing in the healthcare industry. With a strong academic foundation, a B.Sc. in Biotechnology and an MBA in Pharmabiotechnology, she brings a unique blend of scientific understanding and strategy.

Learn more about Shivani Zoting

Aditi Shivarkar, with over 14 years of experience in consumer goods, leads research at Towards Consumer Goods, ensuring precise, actionable insights on trends, consumer preferences, and sustainable packaging for businesses.

Learn more about Aditi Shivarkar

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FAQ's

Thermo Fisher Scientific Inc. is the major player in the market.

Increasing awareness is the factor that drives the market.

Ministry of Health and Family Welfare, Government of India, National Institutes of Health, FDA, WHO, PIB, CDC.