20 June 2025
Image Credits: The Wall Street Journal
Sanofi, a multinational pharmaceutical and healthcare company, has a strong approach to ROFNs in its licensing deal. Vigil, a clinical-stage biotechnology company, is a recent example of Sanofi’s approach. In July 2024, Sanofi provided $40 million in capital to Vigil for reserving ROFN for Alzheimer’s disease asset VG-3927. After eleven months, Sanofi had all it needed and then approached the acquisition of the entire company. Sanofi's intellectual skills and on-time smart decisions are a perfect example for many other biotech and pharma companies. The company’s terms and conditions and strong agreement policy are themselves a strategy to explore and adopt new partnerships.
Apart from Sanofi’s multiple deals, the $27 million investment along with ROFN in Ventyx Biosciences gave Sanofi an exclusive right to be a primary prospect of VTX3232, which is a central nervous system-penetrant NLRP3 inhibitor in Phase ll development. Ventyx is already attracting multiple major callouts for VTX3232 and Parkinson’s diseases, including subjects of obesity and other cardiometabolic risk-related factors, this year.
Ventyx shares rose after Sanofi acquired Vigil by focusing on similar factors of CNS diseases. With ROFN, Sanofi has achieved the right for a certain period to negotiate valuable deals, but the company’s clause does not prohibit other pharma to making an offer. Apart from partnership deals, Sanofi contributed by partnering multiple sclerosis program in October 2024.
As acquisitions and partnerships are a support to the global healthcare sector, such as healthcare services, medical devices, etc. The healthcare market has witnessed various developments in pathology, biotech, and pharma, including other healthcare departments. AbbVie’s optional agreement on Reproxalap, which needs a decision in 10 days after FDA’s approval. The official AbbVie-Aldeyra deal also consists of ROFN for AbbVie.
The licensing deal is mostly a leading company approaching a smaller biotech’s assets for development, but turns out to be weird after diving deeper. The conduit pharma and AstraZeneca partnered in 2024 with the UK pharma company. The company enabled licensing rights to Conduit. But Conduit has a different policy structure, it funds and acquires the development of phase II-ready assets and moves fast towards phase ll without selling rights to a third party if everything goes well.
Jefferies, a provider and investor firm in the healthcare sector, found 50 ROFN agreements in biopharma in the past years that include different clauses with varying results. In addition to Sanofi’s vigil licensing deal, the three outstanding existing agreements from the pharmaceutical company are with MeiraGTx, Ventyx Biosciences, and Zucara.
20 June 2025
20 June 2025
20 June 2025
20 June 2025