Curadev and MSK Expand Partnership to Advance Cancer Immunotherapy with CRD3874-SI

Curadev’s Strategic Collaboration

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Announcement

Curadev Pharma, Inc., a leading clinical-stage biotechnology company, along with Memorial Sloan Kettering Cancer Center (MSK), a global cancer research and treatment institution novel immune-oncology therapeutics expanding its strategic collaboration via the MSK Therapeutics accelerator program. This will help Curadev to accelerate the development of small-molecule allosteric stimulators of interferon genes (STING), prime mover CRD3874-SI. The collaboration initiates a systematic delivery to patients suffering from advanced or metastatic cancer.

Collaboration

The collaboration is based on the current extensive clinical trial (NCT06021626), and phase 1a/b dose escalation, which is in progress at MSK for Merkel and sarcoma cell carcinoma patients. It further focuses on CRD3874-SI's potential to treat other types of cancer. The MSK Therapeutics Accelerator Program will be a source for MSK to provide Curadev institutional resources, expertise, and (clinical, regulatory, medical) advice to contribute to the development of CRD3874-SI. This collaboration encompasses STING research into a larger clinical application. These applications will be under the provision of MBBCh BAO, Interim clinical director of MEK’s sarcoma oncology service, Ciara Kelly, and MD, Chief of the sarcoma medical oncology service at MSK, William Tap.

How is Collaboration Enhancing the Healthcare Market?

The development within the partnership doubles the progress of both entities. So, the MSK Therapeutics accelerator program is a platform to elevate CRD3874-SI performance and appearance. It is a solution that has the potential to be a prominent breakthrough in the global cancer market. This will improve patient care and support healthcare management.

Views and Statements

Dr. William Tap said, “MSK and its division of solid tumors are thrilled to develop CRD3874-SI, a first-in-class allosteric STING with Curadev. The CRD3874-SI has presented an efficient and safe profile in a first-in-human study. A small molecule STING agonist CRD3874-SI applies to multiple solid-tumor expansion cohorts, confirmed by disease-specific experts and the structure and support of the MSK accelerator program. The CRD3874-SI is capable of providing a new treatment option with constant innovation of the advantage of immunotherapy in cancer care.”

Co-founder and CEO of Curadev, Dr. Arjun Surya, said, “We gathered courage from early readouts with CRD3874-SI systematic monotherapy with our clinical trials in patients, along with the treatment-refractory cancers at MSK. This led to an opportunity to strengthen the collaboration via the MSK Therapeutics accelerator program. The idea of collaboration of research and development between inventors of CRD3874-SI at Curadev and oncologists at MSK can be an inspiration to develop advancements in bedside medicines.”