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Next-Gen Proteomics Market Size, Drivers and Key Challenges

Next-Gen Proteomics Market Opportunities and Key Trends

The increasing demand for personalized medicine and drug discovery in proteomics is driving the market expansion. Whereas, North America was dominant in the market, due to growing chronic disease incidences and accelerating advancements in healthcare infrastructure, and a strong life sciences industry.

Category: Biotechnology Insight Code: 5761 Format: PDF / PPT / Excel

The next-gen proteomics market is rapidly advancing on a global scale, with expectations of accumulating hundreds of millions in revenue between 2025 and 2034. Market forecasts suggest robust development fueled by increased investments, innovation, and rising demand across various industries.

The global next-gen proteomics market is experiencing major growth due to factors such as the growing number of chronic disease cases, including cardiovascular conditions, autoimmune disorders, and neurological diseases, which require highly efficient personalized medicine based on individual characteristics. Moreover, various technological advancements like NGS (next-generation sequencing), mass spectrometry, and chromatography techniques are fueling market growth. Also, accelerating the drug discovery process to develop targeted therapies is encouraging investments in the R&D of proteomics.

Key Takeaways

  • North America dominated the global next-gen proteomics market share in 2024.
  • Asia Pacific is expected to be the fastest-growing region during the forecast period.
  • By technology, the mass spectrometry segment led the market in 2024.
  • By technology, the protein microarrays segment is expected to grow at the fastest CAGR in the upcoming years.
  • By product & service, the instruments segment was dominant in the market in 2024.
  • By product & service, the software segment is expected to grow fastest in the predicted timeframes.
  • By application, the drug discovery segment held the largest revenue share of the market in 2024.
  • By application, the personalized medicine segment is expected to be the fastest-growing segment in the studied years.
  • By end user, the pharmaceutical & biotechnology companies segment dominated the next-gen proteomics market in 2024.
  • By end user, the diagnostic laboratories segment is expected to grow at the fastest CAGR over the projected period.

Key Metrics and Overview

Metric Details
Important Highligts NA led in 2024, APAC growing fastest, Mass spectrometry led tech, Protein microarrays growing fastest, Instruments led, Software growing fastest
End User Insights Pharma & biotech led in 2024, Diagnostic labs to grow fastest
Recent Trends Syncell & Spear Bio secured funding & partnerships in 2024–2025
Market Driver Rising demand for personalized medicine and drug discovery
Market Restraint High costs of instruments and data complexity
Market Opportunity Advances in tech like mass spectrometry, microarrays, and bioinformatics

Market Overview

Next-generation proteomics is one of the advanced technologies and methodologies that provides complete analysis of the proteome, the overall set of proteins in a cell or living organism. Most widely used mass spectrometry and novel bioinformatics enable the description of protein expression, structure, and interactions on a huge scale, such as post-translational modifications. The next-generation proteomics market is highly propelled by the accelerating advancements in technologies, increasing developments for personalized medicine, along with this, boosting numerous approaches in drug discovery, and growing public and private investments in research and development of infrastructure.

  • In April 2025, Taiwan-based Syncell, a global player in next-generation subcellular protein purification and spatial proteomics analysis, announced its preferred partner network with Cold Spring Biotech, SCRUM, and DaonBS in Asia Pacific to create new opportunities in proteomics. (Source - biospectrumasia)
  • In December 2024, Syncell, a global leader in next-gen subcellular protein purification and spatial proteomics analysis, announced its $15 million series funding to escalate the global commercial expansion of its protein purification and spatial proteomics technology. (Source - Businesswire)
  • In July 2024, Spear Bio, a biotechnology company, secured $45 million in oversubscribed series financing from Foresite Capital and Bio-Techne Corporation to enhance a product launch for protein research and disease diagnostics. (Source - Businesswire)

How is AI impacting the Next-Gen Proteomics Market?

AI in the respective market provides interpretation of a huge volume of data generated by different technologies, like mass spectrometry and other proteomic techniques. Also, it helps in the identification of subtle patterns and biomarkers indicative of diseases, drug responses, or biological processes. Moreover, AI algorithms unite proteomics data along with other omics data, including genomics, transcriptomics, to allow a more holistic view of biological systems.

For instance,

  • In April 2025, Signios Biosciences, a science-first biotechnology company at the forefront of multiomics and AI-powered bioinformatics, launched an AI-powered bioinformatics and advanced multiomics platform to empower the prospect of precision medicine and drug discovery. (Source - Businesswire)

Market Dynamics

Driver

Growing Demand for Personalized Medicines and the Drug Discovery Process

Globally, nowadays, the next-gen proteomics market growth is driven by the rise of different health conditions requiring tailored medicines based on individual characteristics, in which proteomics plays a major role in the detection of disease-specific biomarkers, recognizing individual protein profiles, and advancing targeted therapies, acting as key components of personalized medicine. Besides this, the rising instrumental target validation, MOA studies, and identification of robust drug candidates, simplifying the drug development process.

Restraint

Boosting the Expenditure on Instruments and Consumables

In the next-gen proteomics market, growing challenges are the increasing expenses on advanced technologies such as mass spectrometers and chromatography systems, with raised spending on their installation and maintenance. This expense generates hurdles for small-scale research labs, academic institutions, and companies. Another is the rising need for expertise to analyze the vast amounts of data and manage complexity.

Opportunity

Progressing Technological Advancements and Bioinformatics

In the upcoming era, different kinds of opportunities are growing, such as innovations in various technologies, including mass spectrometry, protein microarrays, and NGS, which are improving accuracy and acquisition in both research and clinical settings. Moreover, breakthroughs in single-cell analysis and bioinformatics are providing more detailed and complete next-gen proteomic studies.

Segmental Insights

How did the Mass Spectrometry Segment Lead the Next-Gen Proteomics Market in 2024?

By technology, the mass spectrometry segment held the dominating revenue share of the market in 2024. The segment is driven by rising technological advancements, increasing demand for personalized medicines, and enhanced techniques in protein quantification and identification, including 4D proteomics, single-cell proteomics, which also boosts the adoption of mass spectrometry in next-generation proteomics research.

By technology, the protein microarrays segment is expected to grow rapidly during the forecast period. The rising chronic disease cases, growing personalized medicines demand, and breakthroughs in technologies are widely impacting the next-gen proteomics market growth. Furthermore, the segment is expanding due to the accelerating adoption of biomarker discovery, high-throughput screening, and prior disease detection.

What Made the Instruments Segment Dominant in the Market in 2024?

By product & service, the instruments segment led the market in 2024. Along with technological advancements and the drug discovery process, other factors such as rising investments in proteomics R&D and declining expenses of next-generation sequencing (NGS) technologies are escalating their adoption in different approaches, fueling the segment growth.

The software segment is expected to grow at the fastest CAGR in the coming years. The advancing next-generation proteomics technologies, including mass spectrometry and high-throughput screening, are generating large and complex datasets. These datasets require sophisticated software for analysis and interpretation, which results in the demand for specialized bioinformatics tools. Although this software simplifies the workflows, enhances data analysis efficiency, and is user-friendly, it is a plus.

Why did the Drug Discovery Application Lead the Next-Gen Proteomics Market in 2024?

By application, the drug discovery segment held the dominating revenue share of the market in 2024. Due to the analysis of protein expression and interactions, proteomics assists in the identification of specific protein targets for drug intervention, which accelerates the development of targeted therapies with enhanced efficiency. Also, drug discovery supports in finding targets with their cellular pathways effects, with the enhancement of drug efficacy and the reduction of side effects.

By application, the personalized medicine segment is expected to grow fastest during the forecast period. Nowadays, numerous diseases are growing, such as cancer, autoimmune conditions, and cardiovascular diseases, which need customized therapies that rely on individual genetic and proteomic profiles are majorly driving the expansion of the market.

How did the Pharmaceutical & Biotechnology Companies Segment Dominate the Market in 2024?

By end user, the pharmaceutical & biotechnology companies segment led the next-gen proteomics market in 2024. The segment is driven by the rising adoption of drug discovery and personalized medicine. Along with this, growing advancements in technologies are being acquired by many pharmaceutical & biotechnology companies are contributing to the development of next-generation proteomics.

By end user, the diagnostic laboratories segment is expected to grow fastest in the studied years. The expansion of the segment is based on growing advancements in Next-generation sequencing (NGS), CRISPR, and other molecular biology techniques, which enable rapid, affordable, and accurate diagnostic tests, ultimately resulting in early detection of disease and potential personalized choices.

Regional Insights

What made North America dominate the Market in 2024?

North America led the global next-gen proteomics market by capturing the largest revenue share in 2024. The market is propelled by the rising chronic diseases, including age-related disorders, neurological diseases, autoimmune diseases, and cancer, along with increasing well-established healthcare infrastructure and a strong life sciences area. As well as respective governments are encouraging investments in proteomic R&D approaches.

The U.S. Next-Gen Proteomics Market Trends

In the US, the market is driven by accelerating technological advancements like NGS and mass spectrometry, which are boosting the potential and applications of proteomics. Besides this, the major population of this country is demanding precision medicine with the identification of disease biomarkers and drug targets.

The Canada Next-Gen Proteomics Market Trends

Canada, with raised government initiatives and private sector investments, is propelling research and development in next-gen proteomics in domains such as biomarker identification and drug discovery, driving the market growth.

Escalating Chronic Diseases and Demand for Personalized Medicine are Driving Asia Pacific

Asia Pacific is expected to grow at the fastest CAGR in the upcoming years. This regional market is driven by several factors, with the majorly contributor being the rise in the number of cases of chronic diseases, including heart conditions, diabetes, autoimmune disorders, and neurological diseases. Along with this, raised cases are demanding highly efficient personalized medicines in proteomics.

The China Next-Gen Proteomics Market Trends

China is experiencing crucial growth due to boosting innovations in technologies like NGD, mass spectrometry, and bioinformatics, which help in the optimization of sensitivity, precision, and throughput of proteomic analysis. Also, there are surging clinical trials and conventional research efforts that are demanding of proteomics.

The India Next-Gen Proteomics Market Trends

The market in India is propelled by the development of biologics and biosimilars, with its increased application in biomarker discovery for disease detection and prognosis acting as major growth factors. As well as India is accelerating collaborations, partnerships with biopharmaceutical industries, hospitals, and research academics are involved as fuel for market growth.

Growing Awareness and Advancements in Bioinformatics are Driving Europe

In Europe, the significant market growth is impelled by the rising awareness about its adoption in different areas such as oncology, neurology, immunology, and pathology. Also, the advancements in bioinformatics tools and computational techniques are allowing researchers the analyze and interpret complex proteomic data, which is fueling the expansion of the market.

The Germany Next-Gen Proteomics Market Trends

Various academic institutions, biotechnology and pharmaceutical companies with government funding are participating in research activities of proteomics are fueling the market growth.

The UK Next-Gen Proteomics Market Trends

The UK is facing major growth due to the increasing incidence of chronic diseases, the accelerating demand for precision medicines, and the advancements in proteomics technologies.

Top Companies in the Next-Gen Proteomics Market 

Next-Gen Proteomics Market Companies

Latest Announcements by Industry Leaders

  • In June 2025, Thermo Fisher Scientific announced about launch of the Thermo Scientific Orbitrap Astral Zoom mass spectrometer (MS) and the Thermo Scientific Orbitrap Excedion Pro mass spectrometer (MS) to support in catering the boundaries of scientific discovery at ASMS 2025. Marc N. Casper, chairman, president, and chief executive officer of Thermo Fisher, commented that this launch will provide researchers in the worldwide to enhance discovery and advance the revolutionizing of scientific breakthroughs. (Source - Businesswire)
  • In Jun 2024, SPT Labtech, a leading player in the design, development, and manufacture of automated instrumentation and consumables for life science applications, and Olink Holding AB, a supplier of proteomics solutions at unrivaled throughput, announced the launch of a new automation alternative for the Olink® Explore HT protocol for high-throughput proteomics with SPT Labtech’s firefly® liquid handling platform. Joby Jenkins, Chief Technology Officer at SPT Labtech, stated that this new approach will move toward strengthening access to high-throughput and streamlined proteomics workflows. (Source - News)

What are the Recent Developments in the Next-Gen Proteomics Market?

  • In June 2025, Evosep, a biotechnology company, launched Evosep Eno, a novel high-throughput separation platform designed to assist next-generation workflows in liquid chromatography-mass spectrometry (LC-MS)-based proteomics. (Source - Pharmafile)
  • In May 2025, Bruker Corporation launched the timsOmni™ system, a transformative novel timsTOF-based mass spectrometer created for scientific, drug discovery, and clinical researchers, as well as for advanced QC on biologics. (Source - Silicon)
  • In January 2025, Quantum-Si Incorporated, the Protein Sequencing Company™, launched Platinum® Pro, its novel benchtop sequencer that sets a new standard in protein analysis. (Source - Businesswire)

Segments Covered in the Report

By Technology

  • Mass Spectrometry
  • Protein Microarrays
  • X-ray Crystallography
  • NMR Spectroscopy
  • Surface Plasmon Resonance (SPR)
  • Electrophoresis
  • Chromatography
  • Edman Sequencing

By Product & Service

  • Instruments
  • Reagents
  • Software
  • Services

By Application

  • Drug Discovery
  • Clinical Diagnostics
  • Biomarker Discovery
  • Functional Proteomics
  • Disease Diagnostics
  • Personalized Medicine

By End User

  • Pharmaceutical & Biotechnology Companies
  • Academic & Research Institutes
  • Hospitals & Clinics
  • Diagnostic Laboratories
  • CROs (Contract Research Organizations)

By Region

  • North America
    • U.S.
    • Canada
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Thailand
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Sweden
    • Denmark
    • Norway
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East and Africa (MEA)
    • South Africa
    • UAE
    • Saudi Arabia
    • Kuwait
  • Last Updated: 23 June 2025
  • Report Covered: [Revenue + Volume]
  • Historical Year: 2021-2023
  • Base Year: 2024
  • Estimated Years: 2025-2034

Meet the Team

Kesiya Chacko is an accomplished market research professional with over 4+ years of experience in the healthcare industry, known for delivering actionable insights and strategic analysis that empower healthcare organizations.

Learn more about Kesiya Chacko

Aditi Shivarkar, with over 14 years of experience in consumer goods, leads research at Towards Consumer Goods, ensuring precise, actionable insights on trends, consumer preferences, and sustainable packaging for businesses.

Learn more about Aditi Shivarkar

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FAQ's

The global next-gen proteomics market is being driven by a convergence of factors a surge in chronic diseases like cancer, cardiovascular, and autoimmune disorders

Asia Pacific is expected to grow at the fastest CAGR through 2034, fueled by rising healthcare expenditures, expanding R&D infrastructure, and a growing burden of chronic diseases.

Mass spectrometry leads in adoption due to its high precision in protein analysis, while protein microarrays are expected to see the fastest growth due to their utility in biomarker discovery and disease diagnostics

AI enables rapid and accurate interpretation of complex proteomics datasets, identifying biomarkers, predicting drug responses, and integrating multi-omics data.

High capital expenditure for advanced instruments, complex data analysis requiring skilled personnel, and limited accessibility in low-resource settings pose significant challenges.

Pharmaceutical and biotechnology companies are the dominant end-users due to their extensive drug discovery programs and precision medicine initiatives

Next-gen proteomics enables the identification and validation of protein targets, mechanism-of-action studies, and biomarker discovery, significantly shortening drug development timelines.